The vaccine book /
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| Format: | Book |
| Language: | English |
| Published: |
Amsterdam ; Boston :
Academic,
2003.
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Table of Contents:
- 1. Global burden of disease
- A. The burden of vaccine-preventable diseases
- B. Cost effectiveness of immunization : asking the right questions
- C. Potential and existing impact of vaccines on disease epidemiology
- 2. Immunology
- A. Basic immunology of vaccine development
- B. Immunological requirements for vaccines to be used in early life
- 3. Trial design for vaccines
- A. Clinical development of new vaccines : phase 1 and 2 trials
- B. Phase 3 studies of vaccines
- 4. Ethics and vaccines
- 5. Understanding microbial pathogenesis as a basis for vaccine design
- A. Bacteria
- B. Disease-oriented approach to the discovery of novel vaccines
- C. Immunological memory and vaccines against acute cytopathic and noncytopathic infections
- D. Parasitic diseases, with an emphasis on experimental cutaneous leishmaniasis
- 6. Disease states and vaccines : selected cases
- A. Introduction
- B. Polio
- C. Rubella
- D. Pertussis
- E. Rotavirus
- F. Aids vaccines : challenges and prospects
- G. Pneumococcus, pneumococcal disease, and prevention
- H. Tuberculosis
- I. Malaria
- J. Human papillomaviruses
- K. Helicobacter pylori
- L. Genome-based approach for a vaccine against Neisseeria meningitidis
- 7. Economics of vaccines : from vaccine candidate to commercialized product
- 8. Vaccine safety : real and perceived issues
- 9. Introduction of new vaccines in the healthcare system
- 10. Future challenges for vaccines and immunization