Single nucleotide polymorphisms : methods and protocols /

Bibliographic Details
Other Authors: Kwok, Pui-Yan, 1956-
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2003]
Series:Methods in molecular biology ; v.212.
Subjects:
Table of Contents:
  • SNPs : why do we care?
  • Denaturing high-performance liquid chromatography
  • SNP detection and allele frequency determination by SSCP
  • Conformation-sensitive gel electrophoresis
  • Detection of mutations in DNA by solid-phase chemical cleavage method : a simplified assay
  • SNP discovery by direct DNA sequencing
  • Computational SNP discovery in DNA sequence data
  • Genotyping SNPs with molecular beacons
  • SNP genotyping by the 5'-nuclease reaction
  • Genotyping SNPs by minisequencing primer extension using oligonucleotide microarrays
  • Quantitative analysis of SNPs in pooled DNA samples by solid-phase minisequencing
  • Homogeneous primer extension assay with fluorescence polarization detection
  • Pyrosequencing for SNP genotyping
  • Homogeneous allele-specific PCR in SNP genotyping
  • Oligonucleotide ligation assay
  • Invader assay for SNP genotyping
  • MALDI-TOF mass spectrometry-based SNP genotyping