Calcium-binding protein protocols /

Bibliographic Details
Other Authors: Vogel, Hans J.
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2002]
Series:Methods in molecular biology (Clifton, N.J.) ; v. 172.
Methods in molecular biology (Clifton, N.J.) ; v. 173.
Subjects:
Table of Contents:
  • v. 1. Reviews and case studies
  • Calcium-binding proteins
  • Calcium
  • Crystal structure of calpain and insights into Ca²⁺-dependent activation
  • The multifunctional S100 protein family
  • Ca²⁺-binding to proteins containing gamma-carboxyglutamic acid residues
  • The caseins of milk as calcium-binding proteins
  • Preparation of recombinant plant calmodulin isoforms
  • Isolation of recombinant cardiac troponin C
  • Skeletal muscle troponin C : expression and purification of the recombinant intact protein and its isolated N- and C-domain fragments
  • Pruificationof recombinant calbindin D9k
  • S100 proteins : from purification to functions
  • Cadherins
  • Alpha-cactabumin and (calcium-binding) lysozyme
  • Recombinant annexin II tertramer
  • Purification and characterization of ALG-2 : a novel apoptosis-linked Ca²⁺-binding protein
  • Crystalilization and structural details of Ca²⁺-induced conformational changes in the EF-hand domain VI of calpain
  • Neurocalcin : role in neuronal signaling
  • Crystallization and structure-function of calsequestrin
  • Use of fluorescence resonance energy transfer to monitor Ca²⁺-triggered membrane docking of C2 domains
  • Ca²⁺-binding mode of the C₂A-domain of synaptotagmin
  • Study of calcineurin structure by limited peoteolysis
  • v. 2. Methods and techniques
  • Quantitative analysis of Ca²⁺-binding by flow dialysis
  • Calcium binding to proteins studies via competition with chromophoric chelators
  • Deconvolution of calcium-binding curves : facts and fantasies
  • Absorption and circular dichroism spectroscopy
  • Fourier transform infrared spectroscopy of calcium-binding proteins
  • Steady-state fluorescence spectroscopy
  • Fluorescence methods for measuring calcium affinity and calcium exchange with proteins
  • Surface plasmon resonance of calcium-binding proteins
  • Differential scanning calorimetry
  • Isothermal titration calorimetry
  • Multiangle laser light scattering and sedimentation equilibrium
  • Small-angle solution scattering reveals information on conformational dynamics in calcium-binding proteins and in their interactions with regulatory targets
  • Investigation of calcium-binding proteins using electrospray ionization mass spectrometry
  • Synthetic calcium-binding peptides
  • Proteolytic fragments of calcium-binding proteins
  • Electron magnetic resonance studies of calcium-binding proteins
  • Cadmium-113 and Lead 207 NMR spectroscopic studies of calcium-binding proteins
  • Calcium-43 of NMR of calcium-binding proteins
  • Exploring familial relationships using multiple sequence alignment
  • Structure determination by NMR : isotope labeling
  • Protein structure calculation from NMR data
  • Shape and dynamics of a calcium-binding protein investigated by Nitrogen-15 NMR relaxation
  • The use of dipolar couplings for the structure refinement of a pair of calcium-binding EGF domains
  • Vector geometry mapping : a method to characterize the confromation of helix-loop-helix calcium-binding proteins
  • Use of calmodulin antagonists and S-100 protein interacting drugs for affinity chromatography
  • Enzymatic assays to compare calmodulin isoforms, mutants, and chimeras
  • Gene expression in transfected cells
  • Monitoring the intracellular free Ca²⁺-calmodulin concentration with genetically-encoded fluorescent indicator proteins
  • Studying the spatial distribution of Ca²⁺-binding proteins : how does it work for calmodulin