Interleukin protocols /

Bibliographic Details
Other Authors: O'Neill, Luke A. J., Bowie, Andrew
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2001]
Series:Methods in molecular medicine ; 60.
Subjects:
Table of Contents:
  • Pt. I. General methods for assaying interleukin protin and mRNA
  • ELISAs and interleukin research
  • ELISPOT technique for assaying interleukins
  • Measurement of interleukins by ELISPOT assay with particular application to dual-color analysis (stardust assay)
  • Assaying interleukins intracellularly by FACS
  • Basic RT-PCR for measurement of cytokine expression
  • Quantitative PCR for measurement of cytokine expression
  • Single cell RT-PCR for the detection of cytokine mRNA
  • Quantitation of cytokine mRNA by flash-type bioluminescence
  • Measurement of interleukin mRNA by Norther Blotting using a nonradioactive detection method
  • Quantification of mouse IL-6 and TNF-alpha mRNA using Xplore assays
  • Measurement of cytokine and chemokine mRNA using nonisotopic multiprobe RNase protection assay
  • Isolation of total and bioactive interleukins by immunoaffinity-receptor affinity chromatography
  • Detection of cytokines by immunohistochemistry
  • Whole blood assays and the influence of circadian rhythmicity on human cytokine measurement
  • Pt. II. Illustration of methodologies using individual interleukins
  • Assaying interleukin-8
  • Measurement of interleukine-2 by bioassay
  • Assaying interleukin-15
  • Pt. III. Assaying interleukins in particular pathologies
  • Assaying interleukin-6 in breast cancer
  • Cytokines, stress, and depressive illness
  • Measurement of interleukins in cutaneous disorders : competitive RT-PCR for determination of IL-10 mRNA expression in psoriasis
  • Interleukins in Graves' disease
  • Evaluation of cytokines in migraine patients by ELISA
  • Assaying interleukins in plasma in the course of acute myocardial infarction
  • Pt. IV. Assaying interleukins in particular biological fluids
  • Measurement of cytokines in peritoneal fluids
  • Measurement of cytokines in seminal plasma
  • Measurement of cytokines in induced sputum : application to the investigation of asthma and COPD
  • Cytokines in blister fluids
  • Measurement of cytokines in synovial fluid
  • Measurement of cytokines in cerebrospinal fluid
  • Detection of cytokines in tears
  • Pt. V. Newer techniques : interleukin signal transduction, recombinant interleukin production, interleukin gene polymorphisms, and the use of cDNA arrays
  • Measurement of phosphoinositide 3-kinase activation by interleukins
  • Analysis of interleukin-2 signaling using affinity precipitations and polyacrylamide gel electrophoresis
  • Applications for green fluorescent protein in cell signaling
  • Use of Pichia pastoris for production of recombinant cytokines
  • Analysis of single nucleotide polymorphisms in the interleukin-1B gene usint 5' nuclease assays
  • Measurement of cytokine and chemokine gene expression patterns using cDNA array