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Leukocyte recruitment, endothelial cell adhesion molecules, and transcriptional control : insights for drug discovery /

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Bibliographic Details
Other Authors: Collins, Tucker
Format: Book
Language:English
Published: Boston : Kluwer Academic Publishers, [2001]
Subjects:
Leukocytes > immunology.
Endothelium > immunology.
Cell Adhesion Molecules > physiology.
Inflammation Mediators > physiology.
Drug Design.
NF-kappa B > physiology.
Table of Contents:
  • The selectins in leukocyte recruitment
  • Transcriptional regulation of the E-selectin gene
  • The immunoglobulin superfamily in leukocyte recruitment
  • Regulation of intercellular adhesion molecule (ICAM) gene expression
  • Transcriptional regulation of VCAM-1
  • Activation of nuclear factor-kB
  • The basal transcriptional apparatus
  • Therapeutic regulation of leukocyte adhesion molecule expression
  • The NF-kB system and drug discovery