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Brain drug targeting : the future of brain drug development /

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Bibliographic Details
Main Author: Pardridge, William M.
Format: Book
Language:English
Published: New York : Cambridge University Press, 2001.
Subjects:
Brain > metabolism.
Central Nervous System Agents > pharmacokinetics.
Blood-Brain Barrier > physiology.
Drug Delivery Systems > methods.
Drug Design.
Table of Contents:
  • Drug targeting, drug discovery, and brain drug development
  • Invasive brain drug delivery
  • Lipid-mediated transport and carrier-mediated transport of small molecules
  • Receptor-mediated transcytosis of peptides
  • Vector discovery : genetically engineered Trojan horses for drug targeting
  • Linker strategies : the engineering of multifunctional drug formulations
  • Protein neurotherapeutics and peptide radiopharmaceuticals
  • Antisense neurotherapeutics and imaging gene expression in vivo
  • Gene therapy of the brain
  • Blood-brain barrier genomics