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Therapeutic immunology /

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Bibliographic Details
Other Authors: Austen, K. Frank (Karl Frank)
Format: Book
Language:English
Published: Malden, MA : Blackwell Science, [2001]
Edition:Second edition.
Subjects:
Immunotherapy.
Immune System > drug effects.
Table of Contents:
  • Pt. I. Introduction
  • Adaptive immunity
  • Innate immunity and instruction of the adaptive immune response
  • Pt. II. Drugs
  • Cyclophosphamide
  • The purine antagonists : azathioprine and mycophenolate mofetil
  • Methotrexate
  • Immunosupression and immunophilin binding agents : current research and clinical applications
  • Glucocorticoid action
  • Cyclooxygenase inhibitors
  • Antileukotrienes (leukotriene modifiers) in the treatment of asthma
  • Phosphodiesterase inhibitors
  • Tryptase inhibitors
  • 5-aminosalicylic acid (mesalamine) and sulfasalazine
  • Antihistamines (H₁-receptor antagonists)
  • Pt. III. Biologic agents
  • Hematopoietic growth factors
  • Cytokines regulating immune inflammation : interleukin-4, interleukin-10, and interleukin-12
  • The interferons : basic biology and therapeutic potential
  • Interleukin-2 immunostimulation
  • A soluble TNF receptor-Fc fusion protein (etanercept) in the treatment of inflammatory diseases
  • Intravenous immunoglobulin therapy
  • Therapeutic inhibition of complement activation with emphasis on drugs in clinical trials
  • Treatment of angioedema resulting from C1-inhibitor deficiency
  • Inhibitors of tumor necrosis factor
  • Targeting the IL-2 receptor with antibodies or chimeric toxins
  • Monoclonal antibodies to CD3
  • Anti-IgE : immunotherapy for allergic diseases
  • Specific and nonspecific immunotherapy for asthma and allergic diseases
  • Treatment of allergy to insect stings
  • The CD28 T-cell costimulatory pathway : pharmacologic inhibition and augmentation
  • Bacterial vaccines
  • Viral vaccines
  • Blockade of the CD40L/CD40 pathway
  • Pt. IV. Maneuvers
  • Renal transplantation
  • Pancreas transplantation
  • Cardiac transplantation
  • Lung transplantation
  • Hemopoietic stem cell transplantation
  • Cell transplantation
  • Liver transplantation
  • Xenotransplantation
  • Cellular therapy
  • Genetically engineered cancer vaccines
  • Gene therapy for inherited immunodeficiencies
  • Plasmapheresis and immunoadsorption
  • Drug therapy for HIV infection.