Viral vectors : basic science and gene therapy /
| Other Authors: | , |
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| Format: | Book |
| Language: | English |
| Published: |
Natick, MA :
Eaton Publishing/BioTechniques Books,
[2000]
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| Subjects: |
Table of Contents:
- Pt. 1. DNA virus vectors
- Family: Parvoviridae. Genus: Dependovirus (adeno-associated viruses [AAV])
- Gene transfer with adeno-associated virus vectors
- Strategies for production of adeno-associated virus vectors
- Production and purification systems for recombinant adeno-associated virus type-2 vectors
- Utility of rAAV for gene transfer into neurons and other highly differentiated cells
- Adeno-associated virus vectors for genetic immunization
- Family: Parvoviridae. Genus: Autonomous parvoviruses
- Autonomous parvovirus vectors
- Family: Adenoviridae. Genus: Mastadenovirus (mammalian adenoviruses)
- Molecular biology of adenovirus gene therapy vectors
- Helper-dependent adenoviral vectors: a new generation of gene delivery vehicles
- Generation of multiply deleted adenovirus vectors that are helper virus independent
- Adenovirus-mediated gene transfer: in vivo persistence of transduced cells and control of transgene expression
- Molecular conjugate vectors
- Family: Herpesviridae. Genus: Alphasimplexvirus (herpes simplex virus)
- Construction of defective herpes simplex recombinant vectors and helper-dependent amplicons
- Gene transfer using helper virus-free herpes simplex virus type 1 amplicon and hybrid amplicon vectors
- Stable gene transfer using hybrid herpes simplex-Epstein-Barr virus amplicon vectors
- Herpesvirus/retrovirus chimeras for gene delivery
- Gene transfer into brain slices from mouse embryos using herpes simplex amplicons
- Gene transfer into cultured postimplantation mouse embryos using herpes simplex amplicons
- The use of herpes simplex vectors to study Alzheimer's disease neurodegeneration
- Family: Herpesviridae. Subfamily: Gammaherpesvirinae. Genus: Rhadinovirus
- Gamma-2-herpesvirus vectors for investigation of viral pathogenesis and experimental gene transfer
- Family: Herpesviridae. Subfamily: Gammaherpesvirinae. Genus: Epstein-Barr virus
- Application of Epstein-Barr virus and its genetic elements to gene therapy
- Family: Poxviridae. Subfamily: Entomopoxvirinae. Genus: Entomopoxvirus B
- Entomopoxvirus vectors
- Family: Baculoviridae. Genus: Nucleopolyhedrovirus (baculovirus)
- High-efficiency transduction of mammalian cells using baculovirus: practical aspects
- Pt. 2. RNA virus vectors
- Family: Retroviridae. Genus: Oncovirnae (MLV)
- Strategies and mechanisms for retrovirus retargeting
- Efficient production of VSV-G-pseudotyped retrovirus vectors using stable packaging cell lines
- Utility of scaffold attachment regions for enhanced retroviral vector expression in human hematopoietic cells
- Kinetics of transduction using retroviral vectors: enhancement by complex formation with cationic liposomes
- Retrovirally mediated genetic marking of murine and human hematopoietic repopulating cells
- Towards the genetic manipulation of the hematopoietic system: tumor-specific gene therapy strategies
- Family: Retroviridae. Genus: Lentivirinae (HIV)
- Cellular transduction by lentiviral vectors
- Family: Retroviridae. Genus: Spumavirinae (foamy viruses)
- Foamy viruses: molecular features and therapeutic potential
- Aspects of foamy virus vectors: host range and replication-competent vectors
- Family: Orthomyxoviridae. Genus: Influenza virus
- Transfectant influenza viruses as vaccine vectors
- Family: Picornaviridae. Genus: Enterovirus (Poliovirus)
- Picornaviruses as tools for antigen delivery
- Family: Togaviridae. Genus: Alphavirus (Semliki forest virus, sindbis virus)
- Strategies and applications of alphavirus vectors in gene therapy
- Efficient expression of proteins with recombinant alphaviruses
- Pt. 3. General issues
- Gene therapy using viral vectors: strategy and design issues
- Biosafety recommendations for working with viral vectors.