Interindividual variability in human drug metabolism /

Bibliographic Details
Other Authors:	Pacifici, Gian Maria, Pelkonen, R. O. (R. Olavi)
Format:	Book
Language:	English
Published:	London ; New York : Taylor & Francis, 2001.
Subjects:	Pharmaceutical Preparations > metabolism. Drug-Related Side Effects and Adverse Reactions. Genetic Variation.

Table of Contents:

Genetic factors that cause variability in human drug metabolism
Interethnic differences in drug disposition and effects
Development and ageing as sources of variability in drug metabolism
Genetic and environmental factors causing variability in psychotropic drug exposure
Interindividual variability in the metabolism of cardiovascular drugs
Interindividual variability in the metabolism of anti-epileptic drugs and its clinical implications
Variability in the metabolism of levadopa and clinical implications
Interindividual variability in the disposition of anti-HIV drugs
Predictive modelling of in vivo drug interaction from in vivo data : from theory to a computer-based workbench and its experimental validation
Interindividual variation of P450 enzymes in vitro and its causes
Interindividual variability of arylamine N-acetyltransferases
Interindividual variation of UDP-glucuronosyltransferases and drug clucuronidation
Interindividual variability of methyltransferases
Interindividual variability of sulfotransferases
Interindividual variability of glutathione transferase expression