Forensic DNA typing : biology & technology behind STR markers /

Bibliographic Details
Main Author: Butler, John M. (John Marshall), 1969-
Format: Book
Language:English
Published: Amsterdam ; Boston : Academic Press, [2001]
Subjects:

MARC

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300 |a xii, 322 pages :  |b illustrations (some color) ;  |c 25 cm. 
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504 |a Includes bibliographical references and index. 
505 0 |a DNA biology review -- Sample collection and preparation (DNA extraction and quantification) -- The polymerase chain reaction (DNA amplification) -- Commonly used short tandem repeat markers -- Biology of STRs : stutter products, non-template addition, microvariants, null alleles, and mutation rates -- Forensic issues : degraded DNA, PCR inhibition, contamination, and mixed samples -- Additional DNA markers : amelogenin, Y-chromosome STRs, mtDNA, SNPs, Alu repeats -- DNA separation methods : slab-gel and capillary electrophoresis -- DNA detection methods : fluorescent dyes and silver staining -- The Abi prism 310 genetic analyzer -- The hitachi FMBIO II fluorescence imaging system -- STR genotyping issues -- Laboratory validation -- New technologies and automation -- Combined DNA index system (CODIS) and the use of DNA databases -- DNA testing in high profile cases 
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