Handbook of laboratory animal management and welfare /
| Main Author: | |
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| Other Authors: | |
| Format: | Book |
| Language: | English |
| Published: |
Oxford [England] ; Malden, MA, USA :
Blackwell Science,
1998.
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| Edition: | Second edition. |
| Subjects: |
Table of Contents:
- Sect. 1. General
- Training and the personal licence holder
- Contents of home office modules
- Legislation and ethical considerations
- Historical background to the animals (scientific procedures) act 1986
- Legislation controlling use of animals in experimentations in other countries
- Summary of the main provisions of the animals (scientific procedures) act 1986
- Designated establishments
- Personal and project licences
- Assessment of benefit and severity
- Reuse of animals
- Breeding and supplying establishments
- Humane killing
- The Ethics of using animals in experiments
- Statistics of animal usage
- Other relevant legislation
- Record keeping
- Notes to assist in the completion of the personal licence application form.
- Notes to assist in the completion of the project licence application
- Health, safety and security
- Legal framework
- The Reporting of incidents, diseases and dangerous occurrences regulations 1995
- Control of substances hazardous to health regulations 1988
- Genetically modified organisms
- The Hazards
- Allergy to laboratory animals (ala)
- Infection
- Injury
- Miscellaneous health and safety hazards and risks
- Chemical hazards.
- Electrical hazards
- Radiation hazards
- Sharp instruments
- Waste disposal
- Lone working
- Employee security
- Further reading
- Humane methods of killing
- Schedule 1 methods
- Overdose of anaesthetic
- Exposure to carbon dioxide
- Physical methods of euthanasia
- Confirmation of death and disposal of carcases
- Introduction to the principles of animal care and use
- Supply of laboratory animals
- General considerations
- Imported and non-schedule 2 animals
- Wild animals
- Non-human primates.
- Transport of laboratory animals
- Legislation and transport regulations
- General considerations
- Handling laboratory animals
- Recognition of pain and stress in laboratory animals
- What is stress?
- How is pain assessed?
- How to quantify pain
- Introduction to laboratory animal husbandry
- Disease prevention
- Health monitoring
- Conduct of minor procedures
- Removal of blood
- Administration of substances
- Indwelling cannulae, arterial loops and fistulae
- Miscellaneous methods of administration and sampling
- Polyclonal antibody production in laboratory animals
- Polyclonal antibody production using adjuvants.
- Polyclonal antibody production using perforated subcutaneous chambers
- Monoclonal antibody production in laboratory animals
- Anaesthesia
- Choosing an anaesthetic
- Preoperative care
- Pre-anaesthetic drugs
- General anaesthesia
- Inhalation or injection?
- General anaesthetic drugs
- Non-recovery anaesthesia
- Long-term anaesthesia
- Combination techniques
- Local anaesthetics
- Anaesthetic management
- Depth of anaesthesia
- Respiration
- Cardiovascular signs
- Body temperature
- Ocular signs
- Anaesthetic emergencies
- Muscle relaxation in anaesthesia
- Neuromuscular blocking agents
- Monitoring aneaesthesia under neuromuscular block
- Contraindications for the use of neuromuscular blockers
- Postoperative complications associated with the use of neuromuscular blockers.
- Introduction to surgery
- Introduction to surgical pathology
- Inflammation and wound healing
- Types of healing
- Principles of surgery
- Historical perspective
- Principles of asepsis
- Surgical techniques
- Perioperative antibiosis and postoperative wound infections
- Suturing techniques and materials
- Suture patterns
- Muscle layer
- Fat
- Subcutis
- Skin
- Suture materials
- Absorbable sutures
- Non-absorbable sutures
- Tissue adhesives
- Suture needles
- Sizes of suture
- Packaging.
- Postoperative care and analgesia
- Postoperative care
- Fluid selection
- Fluid volume replacement
- Monitoring urine output
- Management of pain
- Use of opioids to control pain
- Use of non-steroidal anti-inflammatory drugs (NSAIDS)
- Local anaesthetics
- Additional considerations in pain management
- Sect. 2. Species
- Behaviour
- Handling
- Housing
- Pain and stress recognition
- Feeding
- Common diseases and health monitoring
- Water
- Useful data
- Environment
- Drug doses for anaesthesia
- Breeding
- Drug doses for analgesia
- Growth
- Small laboratory animals.
- Mouse
- Rat
- Hamster
- Gerbil
- Guinea pig
- Rabbit
- Carnivores
- Dog
- Cat
- Ferret
- Primates
- New world monkeys
- Marmoset
- Squirrel monkey
- Old world monkeys
- Macaques
- Baboon
- Larger domestic species
- Pig
- Sheep and goats
- Other species
- Cattle
- Horses
- Other species
- Wild animals
- General considerations
- Health and safety considerations
- Identification of wild animals
- Drug doses and body size
- Drug doses for wild animals
- Birds.
- Introduction
- Anatomical features
- Physiological features
- Husbandry
- Reproduction
- Handling
- Pain and stress recognition
- Common diseases and health monitoring
- Anaesthesia
- Postoperative care
- AnalgesicsAmphibia
- Introduction
- Anurans
- Housing and environmental conditions
- Hibernation
- Feeding and nutrition
- Breeding
- Growth of larvae
- Common diseases and health monitoring
- Caudata (urodeles)
- Housing and environmental conditions
- Feeding
- Breeding
- Growth of larvae
- Common diseases and health monitoring
- Handling of amphibia
- Anaesthesia of amphibia
- Techniques
- Sect. 3. Directory
- Useful equipment
- Useful addresses
- Useful websites
- Bibliography
- Glossary of terms.