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In vitro toxicology : tenth anniversary symposium of CAAT /

Bibliographic Details
Corporate Author: Johns Hopkins Center for Alternatives to Animal Testing
Other Authors: Goldman, Alan M., Principe, Marilyn L.
Format: Book
Language:English
Published: New York : Mary Ann Liebert, [1993]
Series:Alternative methods in toxicology ; vol. 9.
Subjects:
Toxicology > methods > Congresses.
Animal Testing Alternatives > Congresses.
Table of Contents:
  • Pt. 1. Symposium presentations
  • In vitro approaches to neurotoxicity
  • Cholinergic cell lines as models for testing drug efficacy and toxicity / J.K. Blusztajn ... [et al.]
  • Electrophysiological appproaches to in vitro neurotoxicology / J. van den Bercken ... [et al.]
  • Mechanisms of dermatotoxicity
  • In vitro models to evaluate agents that contribute to cutaneous carcinogenesis / S.H. Yuspa
  • Photoimmunology / S.E. Ullrich
  • Development of new biological components for toxicity testing systems.
  • Immortalization of cells / H.C. Isom and J-M. Hu
  • Draize eye testing alternatives - a perspective / J.P. McCulley and T.J. Stephens
  • A ten-year progress report of the center
  • Pride and prejudice: ten years of CAAT - an industry perspective / S.D. Gettings
  • Alternatives in the 90's: what's next? / H. Spira
  • New technologies
  • Flow cytometry - high speed approaches to detecting cellular structure, mechanism, and function / L.A. Sklar
  • Calcium measurements in the assessment of in vitro toxicity / B.F. Trump ... [et al.].
  • Pt. 2. Poster abstracts
  • Dermal toxicity
  • Inflammatory mediators from reconstituted human skin models treated with formulated cosmetic products / W.E. Dressler ... [et al.]
  • Expression of the antigen presenting cell molecule, B7 in normal human skin / A.A. Gaspari
  • Use of multiple endpoints for assessing chemical insult in an organotypic skin culture / R. Gay ... [et al.]
  • Genotoxicity
  • Development and application of human cell lines expressing individual or multiple human cytochrome P450s / C.L. Crespi ... [et al.].
  • Hepatotoxicity
  • New metabolite profile of tolbutamide in male and female rats. A study with precision-cut liver slices and isolated hepatocytes / P. Dogterom and G. Zbinden
  • In vitro culture of fish hepatocytes and their use to assess marine pollution / M. Faisal and B.J. Rutan
  • Mechanisms
  • Glutathione depletion increases the cytotoxic effect of fumonisin in vitro / C. Azuka ... [et al.]
  • Methods development
  • Evaluation of a group of petrochemicals using clonetics' neutral red bioassay to predict irritancy / R. Barstad ... [et al.].
  • Evaluating teratogen exposure utilizing hsp 27 cDNA / N. Bournias-Vardiabasis, K. Hopkins, and B. Wang
  • Neurotoxicity
  • Multicentre initial validation of a tiered system for the in vitro detection of neurotoxicity / C.K. Atterwill
  • Ocular toxicity
  • Evaluation of two in vitro methods as predictors of ocular irritation of shampoo formulations / L. Bernhofer, C. Juneja, and C.W. Stott
  • Validation
  • The use of normal human keratinocytes and the neutral red uptake bioassay to assess the first 30 MEIC compounds / R.D. Curren ... [et al.].