Genetics /

Bibliographic Details
Other Authors: Friedman, J. M. (Jan Marshall), 1947-
Format: Book
Language:English
Published: Baltimore : Williams & Wilkins, [1996]
Edition:Second edition.
Series:National medical series for independent study.
Subjects:
Table of Contents:
  • Nature of the genetic material
  • Genetics in medicine
  • Structure and function of genes
  • Mitosis and meiosis
  • Chromosome structure
  • Epigenetic control of gene expression
  • Chromosome anomalies
  • General features
  • Numerical alterations
  • Structural alterations
  • Other anomalies
  • Single gene alterations
  • Patterns of inheritance
  • Types and mechanisms of mutation
  • Clinical importance of polymorphisms
  • Ethnic factors in genetic disease
  • Linkage and mapping
  • Linkage
  • Gene mapping
  • Genetic heterogeneity.
  • The Human Genome Project
  • DND diagnosis
  • Techniques for DND analysis
  • Detection of known mutations: direct DND diagnosis
  • Detection of unknown mutations: indirect DND diagnosis
  • DND banking
  • Population genetics
  • Genes in population
  • mutations in populations
  • Effects of medical intervention on disease gene frequencies
  • Biochemical basis of disease
  • Introduction
  • Relationship of genes and proteins
  • Diagnosis of a biochemical disease
  • Genetic and environmental interaction
  • Introduction
  • Pharmacogenetics.
  • Multifactorial inheritance
  • Genetics of common adult disorders
  • Behavioral disorders
  • Congenital anomalies
  • Teratogenesis and mutagenesis
  • Introduction
  • Teratogenesis
  • Mutagenesis
  • Epidemiology of congenital anomalies
  • Cancer and genetics
  • General nature of neoplasia
  • Malignancy as a phenotype
  • Malignancy as a genotype
  • Developmental genetics
  • Embryonic development
  • Sexual differentiation
  • Clinical genetic evaluation
  • Approach to clinical genetics
  • Calculating genetic risks
  • Prenatal diagnosis.
  • Introduction
  • Diagnosic techniques
  • The counseling process
  • Genetic counseling
  • Approach to genetic counseling
  • Genetic screening
  • Treatment of genetic disease
  • Introduction
  • Methods of treating genetic disease
  • Ethical issues in medical genetics
  • Introduction
  • Ethical principles
  • Making decisions in the presence of ethical dilemma
  • Areas of conflict in clinical genetics
  • Case studies
  • Comprehensive exam.