Immunology : an introduction for the health sciences /
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| Other Authors: | , |
| Format: | Book |
| Language: | English |
| Published: |
Roseville NSW, Australia :
McGraw-Hill,
[1995]
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| Subjects: |
Table of Contents:
- The immune system
- Natural immunity
- External barriers
- Humoral factors in natural immunity
- Adaptive immunity
- Humoral components
- Cellular components
- Immunoglobulin and antibodies
- Structure of immunoglobulins
- Immunoglobulin classes
- Immunoglobulin variations
- Isotypic variations
- Allotypic variations
- Idiotypic variations
- Antibody diversity
- Antigen-antibody interactions
- Antigen-antibody binding
- Electrostatic forces
- Van der Waals forces
- Antibody affinity
- Antibody avidity
- Immunodominance and accessibility.
- Antigen-antibody interactions in vitro
- Precipitation reactions
- Precipitation in gels
- Agglutination reactions
- Radioimmunoassay (RIA)
- Enzyme-linked immunosorbent assay (ELISA)
- Immunohistology
- Complement
- The classical complement pathway
- The alternative complement pathway
- Biological consequences of complement activation
- Cells of the immune system
- Peripheral blood leukocytes
- Haemopoiesis
- Cells of the monocyte-macrophage lineage
- Dendritic cells
- Neutrophils
- Eosinophils
- Basophils and mast cells.
- Lymphoid cells
- B lymphocytes
- T lymphocytes
- Large granular lymphocytes
- Lymphoid tissues
- Lymphocyte homing
- Accessory cells
- Cytokines
- Classification of cytokines
- Interferons
- Secretion of interferons
- Antiviral activity
- Biological effects of IFN-α and IFN-†
- Interleukins
- Interleukin 1
- Interleukin 2
- Interleukin 3
- Interleukin 4
- Tumour necrosis factors
- Tumour necrosis factor-α
- Tumour necrosis factor-† (lymphotoxin)
- Colony stimulating factors
- Colony stimulating factor 1.
- Granulocyte colony stimulating factor
- Granulocyte-macrophage colony stimulating factor
- Growth factors
- Transforming growth factor-†
- The major histocompatibility complex
- Inheritance of MHC genes
- Haplotypes
- Tissue typing
- MHC class I
- MHC class I gene family
- Structure of class I molecules
- Synthesis of class I molecules
- Expression of class I molecules
- Regulation of class I expression
- MHC class II
- MHC class II gene family
- Structure of class II molecules
- Synthesis of class II molecules.
- Function of MHC molecules
- Peptide processing and binding
- MHC restriction of the immune response
- Function of non-classical (class Ib) gene products
- MHC associations with disease
- Hypersensitivity
- Type 1-immediate hypersensitivity
- Atopy
- Anaphylaxis
- The Schultz Dale reaction
- The atopic state
- Type II-cytotoxic hypersensitivity
- Rhesus incompatibility
- Type III-immune complex hypersensitivity
- Type IV-delayed/cell-mediated hypersensitivity
- Jones-Mote hypersensitivity
- Type V-stimulatory hypersensitivity.
- Type VI-antibody-dependent cell-mediated cytotoxicity (ADCC)
- Mucosal immunology
- Immunoglobulin A (IgA) system
- Non-IgA antibody systems
- Mucosal-associated lymphoid tissue (MALT)
- Oral tolerance
- Immunity to infection; vaccination
- Natural immunity to infection
- Barriers
- Cellular responses
- Humoral factors
- Adaptive immunity
- Immunity to bacteria
- Role of antibody
- Immunity to fungi
- Immunity to viruses
- Cytolytic virus infection
- Immunity to parasites
- Infections to protozoans
- Vaccination.
- Immunodeficiency
- Classification
- Clinical presentation of immunodeficiency
- Patient screening
- Primary immunodeficiency
- Secondary immunodeficiency
- AIDS
- Transplantation and tumour immunology
- Transplantation
- Graft rejection
- Mechanism of graft rejection
- Role of antibody
- Kidney transplants
- Prevention of rejection
- Tumour immunology
- Tumour antigens
- Anti-tumour immunity
- Failure of the immune response to tumours
- Immunotherapy.