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Methods to assess DNA damage and repair : interspecies comparisons /

Animal information

Bibliographic Details
Corporate Authors: Scientific Group on Methodologies for the Safety Evaluation of Chemicals, International Council of Scientific Unions, International Labour Organisation, World Health Organization, United Nations Environment Programme, International Program on Chemical Safety
Other Authors: Tardiff, Robert G., Lohman, Paul H. M., Wogan, Gerald Norman, 1930-
Format: Book
Language:English
Published: Chichester [England] ; New York : J. Wiley, [1994]
Series:SCOPE report ; 52.
IPCS joint symposia ; 19.
SGOMSEC (Series) ; 8.
Subjects:
DNA Damage.
DNA Repair.
Environmental Exposure.
Mutagens > toxicity.
Carcinogens > toxicity.
Physiology, Comparative.
Table of Contents:
  • Introduction, general conclusions, and recommendations
  • DNA damage
  • DNA repair and mutagenesis
  • DNA repair, mutagenesis, and risk assessment
  • DNA adducts and their consequences / F.A. Beland and M.C. Poirier
  • Nucleotide excision-repair among species / J.H.J. Hoeijmakers and A.R. Lehman
  • Interspecies determinants: bioactivation and inactivation of carcinogens / G.J. Mulder
  • Monitoring cytogenetic damage in vivo / A.T. Natarajan, J.D. Tucker, and M.S. Sasaki.
  • In vivo somatic cell gene mutations in humans / R.J. Albertini, J.A. Nicklas, S.H. Rebison, and J.P. O'Neill
  • DNA repair in specific sequences and genomic regions / L.F. Mullenders and C.A. Smith
  • Molecular analysis of mutations in endogenous genes / H. Vrieling and A.A. van Zeeland
  • Molecular analysis of mutations in shuttle vectors and transgenic animals / M.L. Wood, S.B. Verghis, and J.M. Essigman.
  • Structure-activity relationships (SAR): computerized systems / M.D. Waters, A.M. Richards, J.R. Rabinowitz, H.F. Stack, P.H.M. Lohman, and H.S. Rosenkranz
  • Structure-activity relationships: experimental approaches / E.W. Vogel and J. Ashby.