Burger's medicinal chemistry and drug discovery.

Bibliographic Details
Other Authors: Burger, Alfred, 1905-2000, Wolff, Manfred E.
Format: Book
Language:English
Published: New York : Wiley, 1995-
Edition:Fifth edition /
Subjects:
Table of Contents:
  • v. 1. Principles and practice
  • Drug discovery process
  • Conceptual background and development of medicinal chemistry
  • Management of drug discovery
  • Intellectual property in drug discovery and biotechnology
  • Information science in drug discovery
  • Product development issues
  • Drug absorption, distribution and elimination
  • Drug metabolism
  • Drug allergy
  • Application of structural concepts to the predicition of the carcinogenicity of therapeutic agents
  • From discovery to market: the development of pharmaceuticals
  • Structural medicinal chemistry
  • Three dimensional structure-aided drug design
  • Drug receptors
  • Drug-target binding forces
  • Drug discovery technologies
  • Chemical information computing systems in drug discovery
  • Quantitative analysis of structure-activity relationships
  • Molecular modeling in drug design
  • Application of recombinant DNA technology in medicinal chemistry and drug discovery
  • Mass ligand screening as a tool for drug and development discovery
  • Approaches to the rational design of enzyme inhibitors
  • Analog design
  • Peptidomimetics for drug design
  • Oligonucleotide therapeutics
  • Carbohydrate-based therapeutics
  • Metabolic considerations in prodrug design
  • Natural products as leads for new pharmaceuticals
  • v. 2 - Therapeutic agents
  • Part I - Gastrointestinal drugs
  • Cholinergics
  • Anticholinergic drugs
  • Gastric proton pump inhibitors
  • Part IIA - Cardiovascular drugs, pt 1
  • Cardiac drugs
  • Part IIB - Cardiovascular drugs, pt 1
  • Antihypertensive agents
  • Phenoxyacetic and uricosuric diuretics
  • Diuretic and urcosuric agents
  • Part III - Chemotherapeutic agents, pt 1
  • Aminoglycoside, macrolide, glycopeptide, and miscellaneous antibacterial antibiotics
  • Sulfonamides and sulfones
  • Antimycobacterial agents
  • Antifungal agents
  • v. 3. part. I. CNS drugs
  • General anesthetics
  • Antiparkinsonism drugs
  • Sedatives and hypnotics
  • Anticonvulsants
  • Agents used in neurodegenerative disorders
  • Analgesics.
  • Part II. Male sex hormones and analogs
  • Antiallergic agents
  • Retinoids
  • Insulin analogs
  • v.4. Therapeutic agents
  • Pt. 1. Radiological agents
  • Radiosensitizers and radioprotective agents
  • Pt. 2. Cardiovascular drugs
  • Myocardial infarction agents
  • Endogenous vasoactive peptides
  • Hematopoietic agents
  • Anticoagulants, anthrombotics, and hemostatics
  • Pt. 3. Chemotherapeutic agents
  • Synthetic antibacterial agents
  • Lactam antibiotics
  • Update on antiamebic agent development: clinical results and experience
  • Anthelminitic agents
  • Update on anthelmintic agent development: clinical results and experience
  • Antiamebic agents
  • Chemotherapy of African trypansomiasis
  • Antiviral agents, DNA
  • Pt. 4. Endocrine Drugs
  • Female sex hormones and analogs
  • Agents affecting the immune response
  • v.5 - Therapeutic agents
  • Pt. 1. Chemotherapeutic agents, pt. 3
  • Antimalarial agents
  • Pt. 2. CNS drugs, pt. 2
  • Cognition enhancers, agents, and pharmacodynamic models for alzheimer's disease
  • Antidepressant agents
  • Antianxiety agents
  • Antipsychotic agents
  • Pt. 3. Endocrine drugs, pt. 2
  • Antihistamines, topical ocular
  • Antiinflammatory steroids
  • Agents affecting the action of prostaglandins
  • Agents affecting the action of leukotrienes and thromboxanes
  • Histamine H1 receptor antagonists
  • Antiviral agents, RNA viruses other than HIV
  • Pt. 4. Radiological agents, pt. 2
  • Radiopaques