A Clinician's guide to chemotherapy pharmacokinetics and pharmacodynamics /

Bibliographic Details
Other Authors:	Grochow, Louise B., Ames, Matthew M.
Format:	Book
Language:	English
Published:	Baltimore : Williams & Wilkins, [1998]
Subjects:	Antineoplastic Agents > pharmacokinetics. Antineoplastic Agents > pharmacology.

Table of Contents:

Sect. 1. Variations in drug disposition
Individualized dosing of cancer drugs and the role of therapeutic monitoring / Louise Grochow
Pharmacogenetics and polymorphisms / Richard Weinshilboum
Relationship of age to the disposition and effects of anticancer drugs / Louise Grochow and Sharyn Baker
Protein binding: assessment and importance / Clinton Stewart
Pharmacokinetics of drug delivery to the central nervous system / Mahendra Patel, Susan Blaney, Frank M. Balis
Sect. 2. Specific drugs and classes.
Anthracyclines / Jacques Robert
Bleomycin / Robert T. Dorr
Busulfan / Moustapha Hassan
Cytosine arabinoside and cytidine analogs / Vassilios I. Avramis
Oxazaphosphorines: cyclophosphamide and ifosfamide / G.P. Kaijser and Jos H. Beijnen
Epipodophyllotoxins / Howard L. McLeod and William E. Evans
Fluorinated Pyrimidines / Gerard Milano and Marie-Christine Etienne
Hydroxyurea / Peter R. Gwilt
Methotrexate and other antifolates / William Crom
Nitrosoureas / Roy Jones ... [et. al.]
Cisplatin, carboplatin, and platinum analogs / Pierre R. Canal
Paclitaxel and docetaxel / Mary Relling and Daryl Sonnichsen.
Procarbazine, dacarbazine, temozolamide / Brenda J. Foster
6-Mercaptopurine and 6-Thioguanine / Gary R. Erdmann
Thiotepa / Bjorn Hagen
Camptothecan analogues: topotecan and irinotecan / Elora Gupta and Mark J. Ratain
Vinblastine, Vincristine, and Vinorelbine / Dominique Leveque, Francois Jehl, Henri Monteil
Mitomycin C. nitrogen mustard, chlorambucil, and melphalan / Jaap Verweij and J. H. M. Schellens
Sect. 3. Pharmacokinitic and pharmacodynamic methodology
Assay methodology / Joel M. Reid and Matthew M. Ames
Noncompartmental pharmacokinetic analysis / Dennis A. Noe
Population approaches to estimation / Nancy C. Sambol and Romain Sechaud.