Good manufacturing practices for pharmaceuticals : a plan for total quality control /

Bibliographic Details
Main Author: Willig, Sidney H., 1919-
Other Authors: Stoker, James R.
Format: Book
Language:English
Published: New York : Marcel Dekker, [1997]
Edition:Fourth edition, revised and expanded.
Series:Drugs and the pharmaceutical sciences ; v. 78.
Subjects:
Table of Contents:
  • Status and applicability of U.S. regulations: current good manufacturing practices in manufacturing, processing, packaging, and holding of drugs
  • Finished pharmaceuticals: general provisions (subpart A)
  • Organization and personnel: (subpart B)
  • Buildings and facilities: (subpart C)
  • Equipment: (subpart D)
  • Control of components and drug product containers and closures: (subpart E)
  • Production and process controls: (subpart F)
  • Packaging and labeling control: (subpart G)
  • Holding and distribution: (subpart H).
  • Laboratory controls: (subpart I)
  • Records and reports: (subpart J)
  • Returned and salvaged drug products: (subpart K)
  • Repackaging and relabeling
  • The inspection procedure for compliance in the United States: the regulatee is inspected; the rationale for inspection: (21 USC 373, 374)
  • Recalls and CGMPs: enforcement alternatives in the United States
  • Controlled substances safeguards: (21 CFR 1300, et seq.)
  • Who is the manufacturer? Some additional considerations for the multinational.
  • Bulk pharmaceutical chemicals
  • FDA pre-approval inspections/investigations
  • Other GMPs
  • Other approaches to quality
  • Import and export of pharmaceuticals and other products subject to CGMPs
  • Appendix A: Potable water requirements: (40 CFR 141)
  • Appendix B: Components/Repackagers
  • Appendix C: Hearing procedures when FDA proposes the imposition of civil money penalities
  • Appendix D: Section 601.12 changes currently considered "important" by CBER.