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Protein electron transfer /

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Bibliographic Details
Other Authors: Bendall, D. S.
Format: Book
Language:English
Published: Oxford, UK ; Herndon, VA : Bios Scientific Publishers, 1996.
Subjects:
Proteins > metabolism.
Electron Transport.
Biological Transport.
Table of Contents:
  • Outline of theory of protein electron transfer / C.C. Moser and P.L. Dutton
  • Fundamental tunnelling theory
  • Tunnelling in proteins
  • Redox protein engineering principles
  • The protein bridge between redox centres / D.N. Beratan and J.N. Onuchic
  • Tunnelling pathways in proteins
  • Key role for hydrogen bonds predicted
  • Predictions of the tunnelling pathway model
  • Beyond the single pathway view
  • Current challenges
  • Interprotein electron transfer / D.S. Bendall
  • Kinetics of electron transfer reactions in solution.
  • Diffusional kinetics of complex formation
  • The nature of diffusional encounter
  • Ionic strength effects
  • Binding forces and binding energies
  • Non-covalent sources of binding energy
  • Specificity and binding energy
  • Statics and dynamics of reaction complexes
  • The static view
  • The dynamic view
  • Computer modelling of protein-protein interactions / S.H. Northrup
  • Model building of electron transfer complexes
  • Diffusional dynamics of protein-protein association
  • Alternative docking geometries for electron transfer
  • Theoretical methodologies.
  • Modelling of protein structure
  • Calculation of protein electrostatic fields
  • Brownian dynamics equation of motion
  • Results
  • Cytochrome reaction rate constants with distance cut-off model
  • Protein-protein docking in the cytochrome c-CCP reaction
  • CDNP-derivatized cytochrome c reactions with CCP
  • Extension to surface side chain flexibility
  • Treatment of the cytochrome c-CCP reaction with self-consistent electrostatics
  • Structure of electron transfer proteins and their complexes / F.S. Mathews and R.C.E. Durley.
  • Cytochromes and cupredoxins
  • Two-site proteins
  • Ascorbate oxidase
  • Flavocytochromes
  • Complexes between redox proteins
  • Complex of MADH with amicyanin and cytochrome c-551i
  • Cytochrome c peroxidase
  • Activity of crystals
  • Complex dynamics
  • Photosynthetic bacterial reaction centres / W.W. Parson
  • Reaction centre structures
  • Charge separation and competing reactions
  • Kinetics and mechanism of the initial charge separation
  • Calculations of interaction matrix elements and radical pair energies.
  • Copper proteins / O. Farver
  • Ligand structure
  • Redox potentials and spectroscopic properties
  • Role of ligand geometry on ET
  • ET pathway calculations
  • Pathways in protein-protein ET
  • Azurin
  • ET in type-2 copper proteins
  • Haemoproteins / G.R. Moore
  • Structures of haems
  • Tertiary structures of haemoproteins
  • Control of redox potentials
  • Intraprotein electron transfer
  • Electron transfer complexes coupled to ion translocation / P.R. Rich
  • Principles of coupling
  • The chemiosmotic theory
  • The vectorial redox loop.
  • Protein structure and the proton well
  • Electron transfer reactions in chemistry. Theory and experiment / R.A. Marcus
  • Electron transfer experiments since the late 1940s
  • Appendices: Electron transfer rate calculations / F.N. Onuchic and D.N. Beratan
  • The ET Hamiltonian
  • Two-level systems
  • Rate expressions
  • Kinetic analysis / D.S. Bendall
  • Observed rate constants
  • Kinetic models
  • Reversible reactions
  • Two binding sites and rearrangement
  • Ionic strength effects.