Veterans and Agent Orange : update 1996 /
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| Format: | Book |
| Language: | English |
| Published: |
Washington, D.C. :
National Academy Press,
1996.
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| Subjects: |
Table of Contents:
- Executive summary
- Organization and framework
- Toxicology summary
- Exposure assessment
- Veterans and agent orange: the initial IOM report
- Background
- Impact of the report
- Military use of herbicides in Vietnam
- Toxicology
- Summary of VAO
- Literature update
- Update of toxicity profiles
- Methodologic considerations in evaluating the evidence
- Questions to be addressed
- Are herbicides statistically associated with the health outcome?
- What is the increased risk of the disease in question among those exposed to herbicides in Vietnam?.
- Issues in evaluating the evidence
- Experimental studies
- Epidemiologic studies
- The role of case studies and other studies with no comparison groups
- Publication bias
- The role of judgement
- Summary of the evidence
- Categories of association
- Exposure assessment
- Exposure assessment in the evaluation of epidemiologic studies
- Estimates of exposure to herbicides and TCDD during Vietnam service
- TCDD half-life investigations
- TCDD exposure levels for selected epidemiologic studies
- Epidemiologic studies
- Occupational studies.
- Environmental studies
- Vietnam veterans
- Cancer
- Plausibility data
- Expected number of cancer cases among Vietnam veterans in the absence of any increase in risk due to herbicide exposure
- Gastrointestinal tract tumors
- Hepatobiliary cancers
- Nasal/nasopharyngeal cancer
- Respiratory cancers
- Bone cancer
- Soft-tissue sarcomas
- Skin cancers
- Cancers of the female reproductive system
- Breast cancer
- Prostate cancer
- Renal, bladder, and testicular cancers
- Renal cancer
- Bladder cancer
- Testicular cancer.
- Brain tumors
- Summary of VAO
- Malignant lymphomas and myeloma
- Non-Hodgkin's lymphoma
- Hodgkin's disease
- Multiple myeloma
- Leukemia
- Overall summary for cancer
- Health outcomes with sufficient evidence of an association
- Latency and cancer risk
- Analysis of latency in epidemiologic studies
- Results of the literature review of herbicide exposure and cancer
- Reproductive effects
- Fertility
- Spontaneous abortion
- Stillbirth
- Birth defects
- Childhood cancer.
- Neurobehavioral disorders
- Cognitive and neuropsychiatric effects
- Motor/coordination dysfunction
- Chronic persistent peripheral neuropathy
- Acute and subacute transient peripheral neuropathy
- Conclusions for neurobehavioral disorders
- Other health effects
- Chloracne
- Porphyria cutanea tarda
- Respiratory disorders
- Immune system disorders
- Other metabolic and digestive disorders
- Diabetes Mellitus
- Liver toxicity
- Lipid abnormalities
- Gastrointestinal ulcers
- Circulatory disorders
- Summary of VAO
- Update of scientific literature.
- Appendixes: Information gathering
- Risk of disease in Vietnam veterans / Bryan Langholz and Malcolm Pike
- Committee and staff biographies.