The use of SCID mice in the investigation of human autoimmune disease /

Bibliographic Details
Main Author:	Taylor, Peter C.
Format:	Book
Language:	English
Published:	Austin : R.G. Landes, 1994.
Series:	Molecular biology intelligence unit.
Subjects:	Autoimmune Diseases > immunology. Immune System > pathology. Mice, SCID. Chimera.

Table of Contents:

Severe combined immunodeficient mouse
Severe combined immunodeficiency (SCID) syndromes
SCID mouse mutant
SCID mouse phenotype
Genetic nature of the SCID defect
B and T cell leakiness in the SCID mouse
Xenogeneic-SCID chimeras
SCID-hu model
Hu-PBL-SCID model
Study of organ-specific autoimmune disease in xenogeneic-SCID mouse chimeras
Primary biliary cirrhosis
Autoimmune thyroid disease
Myasthenia gravis
Multiple sclerosis
Autoimmune hemolytic anemia
Myocarditis
Diabetes mellitus
Pemphigus vulgaris.
Study of nonorgan-specific autoimmune diseases in xenogeneic-SCID chimeras
Rheumatoid arthritis
Systemic lupus erythematosus
Scleroderma
Sjogren's syndrome
Importance and limitations of the current use of xenogeneic-SCID chimeras in the study of human autoimmune disease
Potential limitations of the current use of xenogeneic-SCID chimeras
New immunodeficient mouse strains.