Therapeutic immunology /

Bibliographic Details
Other Authors: Austen, K. Frank (Karl Frank)
Format: Book
Language:English
Published: Cambridge, Mass., USA : Blackwell Science, [1996]
Subjects:
Table of Contents:
  • Pt. 1. Introduction
  • The immune system 3
  • Endothelial cells in immune inflammation
  • Pt. 2. Drugs
  • Antimetabolites and radiomimetics
  • Cyclophosphamide
  • The purine antagonists: azathioprine and mycophenolate mofetif
  • Methotrexate
  • Progress in therapeutic immunosuppression: cyclosporine, tacrolimus(FK506), and rapamycin
  • Corticosteroids
  • Glucocorticoid hormone action
  • Immunosuppressive and anti-inflammatory actions of corticosteroids
  • Anti-inflammatory agents
  • Cyclo-oxygenase inhibitors
  • receptor site blockers
  • 5-lipoxygenase inhibitors
  • Phosphodiesterase inhibitors
  • Sulfasalazine and 5-aminosalicylic acid.
  • Histamine, antihistamines, and the immune response
  • Drug theray for AIDS
  • Drug therapy for acquired immunodeficiency syndrome
  • Pt. 3. Biologic agents
  • Cytokines
  • Hematopoietic growth factors
  • Cytokines that regulate immune inflammation: interleukin-4, -10, and -12
  • The interferons: basic biology and therapeutic potential
  • Interleukin-2 immunotherapy
  • Interleukin-1 receptor antagonist
  • Macromolecules
  • Intravenous immunoglobulin therapy
  • Immunoglobulin A.
  • The use of recombinant, soluble forms of the membrane complement C3 receptors, CR1 and CR2, as inhibitors of serum complement activation and function
  • Treatment of angioedema resulting from C1 inhibitor deficiency
  • Antibody-based therapy
  • Production and manipulation of antibodies and T-cell receptors using recombinant DNA technology
  • Clinical applications of antileukocyte adhesion molecule monoclonal antibodies
  • Antibody therapies of drug overdose
  • Anti-idiotype-based therapies
  • Immunotherapy of allergic disease
  • Chimeric proteins
  • Immunotoxins.
  • Cytokine toxin fusion proteins
  • Immunoligands: CTLA41g and the CD28 -t-cell costimulatory pathway
  • Vaccines and peptide therapy
  • Bacterial vaccines
  • Oral administration of antigens
  • Vaccine therapies for acquired immunodeficiency syndrome
  • Pt. 4. Maneuvers
  • Transplantation
  • Therapeutic approach to organ transplantation
  • Renal Transplantation
  • Pancreas transplantation
  • Cardiac transplantation: recipient selection and management
  • Lung transplanation
  • Bone marrow and hemopoietic stem cell transplanation
  • Cell transplantation
  • Liver transplantation
  • Xenotransplantation.
  • Cellular therapy
  • Stem cell therapy
  • Cytokine gene-transduced tumor vaccines
  • Gene therapy
  • Gene therapy for inherited immunodeficiencies
  • Adjuvant therapy
  • Adjuvants
  • Extracorporeal therapy
  • Extracorporeal photochemotherapy: Cellular therapy for cutaneous T-cell lymphoma, selected autoimmune disorders, and organ transplant rejection
  • Additional inverventions
  • Tolerogenic peptides
  • Plasmapheresis and immunoadsorption.