http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
International Agency for Research on Cancer
Exposure monitoring -- Occupational exposure of workers to 1,3-butadiene -- Occupational scene of styrene -- Exposure to styrene in the general Canadian population -- Dose measurement -- Interspecies differences in metabolism and kinetics of 1,3-butadiene, isobutene and styrene -- Research strategy for assessing target tissue dosimetry of 1,3-butadiene in laboratory animals and humans -- Species differences in metabolism of 1,3-butadiene in vivo -- Pharmacokinetic model to describe toxicokinetic interactions between 1,3-butadiene and styrene in rats -- Kinetics of urinary excretion and effects on colour vision after exposure to styrene -- Dose-dependent kinetics of inhaled styrene in man -- Characterization of human cytochrome P450 isozymes responsible for styrene metabolism -- ³²P-postlabelling of DNA adducts of styrene oxide-modified DNA and in workers exposed to styrene -- Estimating internal dose of 1,3-butadiene.
(cont) Use of haemoglobin adducts for biomonitoring exposure to 1,3-butadiene -- Biological monitoring of 1,3-butadiene -- Biomonitoring of exposure to 1,3-butadiene -- Neurotoxicity and reproductive effects -- Neurotoxicity in workers exposed to styrene -- Effects of styrene on the reproductive health of women -- Male-mediated F₁ effects in mice exposed to 1,3-butadiene -- Genetic toxicity -- Genetic toxicity of 1,3-butadiene and styrene -- Mutagenicity of 1,3-butadiene and its epoxide metabolites in human TK6 cells and in splenic T cells isolated from exposed B6C3F1 mice -- Toxicity of 1,3-butadiene to bone marrow mimics haematopoietic defects observed in mice bearing steel or white spotted mutations -- Cytogenetic studies of rodents exposed to styrene by inhalation -- Studies of the induction of chromosomal aberration and sister chromatid exchange in rats exposed to styrene by inhalation.
(cont) Use of transgenic mice for assessing the mutagenicity of 1,3-butadiene in vivo -- DNA binding and stimulation of cell division in the carcinogenicity of styrene 7,8-oxide -- Elevated somatic cell mutant frequencies and altered DNA repair responses in nonsmoking workers exposed to 1,3-butadiene -- Susceptibility to induction of chromosomal damage by metabolites of 1,3-butadiene and its relationship to spontaneous sister chromatid exchange frequencies in human lymphocytes -- Cytogenetic studies of workers exposed to styrene -- Cancer mortality in an international cohort of workers exposed to styrene -- Cancer incidence in the Danish reinforced plastics industry -- 1,3-butadiene induces cancer in experimental animals at all concentrations from 6.25 to 8000 parts per million -- Styrene and styrene oxide -- Time-to-tumour risk assessment for 1,3-butadiene based on exposure of mice to low doses by inhalation -- Cancer mortality among workers at a butadiene production factility.
(cont) Cancer epidemiology of styrene-butadiene rubber workers -- Critical assessment of epidemiological studies on the carcinogenicity of 1,3-butadiene and styrene -- Risk assessment and industrial health: evaluating the carcinogenic risk of 1,3-butadiene and styrene.
Selected papers presented at a symposium, held on 18-21 April 1993 in Espoo, Finland.
At head of title: World Health Organization.
Includes bibliographical references and indexes.