Understanding antibacterial action and resistance /

Bibliographic Details
Main Author: Russell, A. D. (Allan Denver), 1936-
Other Authors: Chopra, I. (Ian), 1946-
Format: Book
Language:English
Published: London ; New York : Ellis Horwood, 1996.
Edition:Second edition.
Subjects:
Table of Contents:
  • General nature and development of antibacterial agents
  • Structure of bacteria
  • Structure of spores
  • Mode of action of antibiotics and their uptake into bacteria
  • Inhibitors of nucleic acid synthesis
  • Inhibitors of protein synthesis
  • Antibiotics that inhibit peptidoglycan synthesis
  • Antibiotics that inhibit membrane integrity
  • Antimycobacterial drugs
  • Uptake of antibiotics by bacteria.
  • Antiseptics, disinfectants and preservatives: their properties, mechanisms of action and uptake into bacteria
  • Factors influencing activity
  • General classification of biocides
  • Properties and mechanisms of action of agents interacting with outer cell components
  • Properties and mechanisms of action of membrane-active agents
  • Agents interacting with cytoplasmic constituents: properties and mechanism of action
  • Combination of biocides
  • Uptake of biocides by bacteria
  • Mechanisms of actions: general conclusions.
  • Sporistatic and sporicidal agents: their properties and mechanisms of action
  • Sporulation
  • Germination
  • Outgrowth
  • Mechanisms of action of sporistatic and sporicidal agents
  • Genetic and biochemical basis of acquired resistance to chemotherapeutic antibiotics
  • Resistance to inhibitors of nucleic acid synthesis
  • Resistance to inhibitors of protein synthesis
  • Resistance to antibiotics that inhibit peptidoglycan synthesis.
  • Resistance to antibiotics that inhibit membrane integrity- polymyxin
  • Resistance to antimycobacterial drugs
  • Genetic and biochemical basis of resistance to antiseptics, disinfectants and preservatives
  • Intrinsic biocide resistance
  • Acquired biocide resistance
  • Mechanisms of spore resistance to biocides
  • Experimental aspects
  • Revival of injured spores
  • Impact on society of bacterial resistance to antibiotics and biocides and ways of counteracting it.
  • Impact of bacterial resistance to chemotherapeutic antibiotics
  • Strategies for counteracting resistance to chemotherapeutic antibiotics
  • Impact of bacterial resistance to antiseptics, disinfectants and preservatives
  • Strategies for counteracting resistance to biocides
  • Impact of spore resistance on society
  • Strategies for counteracting resistance of spores to chemicals.