http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Understanding antibacterial action and resistance
General nature and development of antibacterial agents -- Structure of bacteria -- Structure of spores -- Mode of action of antibiotics and their uptake into bacteria -- Inhibitors of nucleic acid synthesis -- Inhibitors of protein synthesis -- Antibiotics that inhibit peptidoglycan synthesis -- Antibiotics that inhibit membrane integrity -- Antimycobacterial drugs -- Uptake of antibiotics by bacteria.
Antiseptics, disinfectants and preservatives: their properties, mechanisms of action and uptake into bacteria -- Factors influencing activity -- General classification of biocides -- Properties and mechanisms of action of agents interacting with outer cell components -- Properties and mechanisms of action of membrane-active agents -- Agents interacting with cytoplasmic constituents: properties and mechanism of action -- Combination of biocides -- Uptake of biocides by bacteria -- Mechanisms of actions: general conclusions.
Sporistatic and sporicidal agents: their properties and mechanisms of action -- Sporulation -- Germination -- Outgrowth -- Mechanisms of action of sporistatic and sporicidal agents -- Genetic and biochemical basis of acquired resistance to chemotherapeutic antibiotics -- Resistance to inhibitors of nucleic acid synthesis -- Resistance to inhibitors of protein synthesis -- Resistance to antibiotics that inhibit peptidoglycan synthesis.
Resistance to antibiotics that inhibit membrane integrity- polymyxin -- Resistance to antimycobacterial drugs -- Genetic and biochemical basis of resistance to antiseptics, disinfectants and preservatives -- Intrinsic biocide resistance -- Acquired biocide resistance -- Mechanisms of spore resistance to biocides -- Experimental aspects -- Revival of injured spores -- Impact on society of bacterial resistance to antibiotics and biocides and ways of counteracting it.
Impact of bacterial resistance to chemotherapeutic antibiotics -- Strategies for counteracting resistance to chemotherapeutic antibiotics -- Impact of bacterial resistance to antiseptics, disinfectants and preservatives -- Strategies for counteracting resistance to biocides -- Impact of spore resistance on society -- Strategies for counteracting resistance of spores to chemicals.
Includes bibliographical references and index.