Bioavailability in environmental risk assessment /

Bibliographic Details
Main Author:	Hrudey, S. E. (Steve E.)
Other Authors:	Chen, W. (Weiping), Rousseaux, Colin George, 1954-
Format:	Book
Language:	English
Published:	Boca Raton : Lewis Publishers, [1996]
Subjects:	Biological Availability. Hazardous Substances > adverse effects. Hazardous Substances > pharmacokinetics. Hazardous Waste. Risk Assessment.

Table of Contents:

Fundamental concept of bioavailability
Definition of bioavailability
Bioavailability in health risk assessment
Mechanism of absorption
Respiratory system
Gastrointestinal system
Skin
Experimental methods for evaluating bioavailability
General in vivo methods
Specific methods for the inhalation exposure route
Specific methods for ingestion exposure route
Specific methods for dermal exposure route
Exposure routes and bioavailability factors for selected contaminants
Arsenic.
Cadmium
Chromium and chromium compounds
Copper
Mercury
Lead
2,3,7,8-tetrachlorodibenzo-dioxin (TCDD)
Polynuclear aromatic hydrocarbons (PAHs)
Benzene
Toluene
Polychlorinated phenols: pentachlorophenol, 2,4,5-trichlorophenol, 2,4,6-trichlorophenol, 2,3,4,5-tetrachlorophenol
Phenol
Aniline
Bioavailability of xenobiotics from contaminated sites
Identification of exposure routes
Reliability and validity of the bioavailability factors
Priority needs for further research.
Considerations for applying bioavailability to health risk assessment
Metals
Organic xenobiotics
Other application considerations
Risk management considerations.