Cytokines in severe sepsis and septic shock /
| Other Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Basel ; Boston :
Birkhäuser Verlag,
c1999.
|
| Series: | PIR (Series)
|
| Subjects: |
Table of Contents:
- Endotoxin as an inducer of cytokines
- Acute lung inflammation in septic shock of the cytokine release induced by bacterial superantigens
- Lipopolysaccharide signaling pathways and their role in the development of the systemic inflammatory response syndrome
- Predisposing factors
- Predisposing factors: effect of sex, nutritional factors and age on immunity following shock and sepsis
- Genetics: cytokine polymorphisms
- Diagnostic
- Possibilities and problems of cytokine measurements
- Soluble TNF receptors
- Relevance of surrogate tests in intensive care patients or "Heisenberg at the ICU"
- Actions (selected events)
- Nitric oxide and endothelin-1 in circulatory shock involving cytokines
- Multistep processes in neutrophil homotypic aggregation and tissue injury
- Cytokines, coagulation and fibrinolysis
- Apoptosis: its role in the systemic inflammatory response syndrome and the involvement of cytokines
- Importance of cytokine metabolism for malnutrition, catabolism and endocrinological state in sepsis
- Therapy
- Endotoxin scavengers as a therapeutic strategy for sepsis
- Interfering with the production of cytokines in sepsis
- Neutralizing antibodies and receptor constructs
- Immunomodulation following shock and sepsis
- Gene therapy, an alternative approach for anti-cytokine therapies
- The failure of clinical trials in sepsis
- The failure of clinical trials in sepsis: challenges of pre-clinical models
- The failure of clinical trials in sepsis: challenges of clinical trial design.