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|a 0387987509 (alk. paper)
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|a 612.3/98
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| 100 |
1 |
|
|a Welle, Stephen.
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| 245 |
1 |
0 |
|a Human protein metabolism /
|c Stephen Welle.
|
| 264 |
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1 |
|a New York :
|b Springer,
|c [1999]
|
| 264 |
|
4 |
|c ©1999
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| 300 |
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|a xi, 288 pages :
|b illustrations ;
|c 25 cm.
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| 338 |
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|a volume
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| 504 |
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|a Includes bibliographical references (pages 228-281) and index.
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| 505 |
0 |
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|a Importance of protein dynamics -- Protein structure and the concept of protein turnover -- Rapid turnover of proteins facilitates rapid changes in protein concentrations -- Protein turnover is necessary to maintain protein quality -- Appendix -- Basic mechanisms of protein turnover -- Protein degradation -- Disposal of amino acids generated by proteolysis -- Protein synthesis -- Posttranslational modifications -- Mitochondrial protein synthesis -- Potential sites of regulation of protein turnover -- Methods for studying protein metabolism in humans -- Measuring changes in protein mass of the body -- Whole-body protein turnover -- Whole-body protein oxidation -- Protein metabolism in specific organs or limbs -- Incorporation of tracer into tissue proteins or specific proteins -- Polyribosome abundance as a measure of protein synthesis -- 3-methylhistidine excretion as a measure of myofibrillar proteolysis -- Markers of collagen metabolism -- Radioiodinated protein administration to measure protein half-life -- Analytical methods -- Normative data from infancy to old age -- Whole-body N balance -- Protein oxidation -- Whole-body protein turnover -- Protein turnover in organs and tissues -- Turnover of specific proteins -- Nutritional influences -- Acute responses to meals -- Starvation -- Very-low-energy diets -- Malnutrition -- High energy intake -- High protein intake -- Summary of effects of energy and protein on whole-body protein metabolism -- Endocrine, paracrine, and autocrine regulation -- Insulin -- Growth hormone -- Insulin-like growth factor-I (IGF-1) -- Other growth factors -- Androgens -- Ovarian steroids -- Epinephrine -- Cortisol -- Thyroid hormones -- Glucagon -- Cytokines -- Prostaglandins -- Regulation by metabolic substrates -- Amino acids -- Glucose and its metabolites -- Triglycerides, fatty acids, and ketone bodies -- Physical activity -- Effect of inactivity on protein metabolism -- Effect of increased physical activity on protein metabolism -- Topics of clinical interest -- Acidosis -- Alcoholism -- Arthritis -- Cancer -- Cirrhosis -- Diabetes -- Glucocorticoid therapy -- Heart disease -- HIV infection and AIDS -- Infection -- Muscular dystrophies -- Obesity -- Parenteral and enteral nutrition -- Pregnancy and lactation -- Renal failure -- Tissue injury (trauma, surgery, burns).
|
| 650 |
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|a Proteins
|x metabolism.
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|a Texas A&M University
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