Cell therapy : stem cell transplantation, gene therapy, and cellular immunotherapy /
| Other Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Cambridge ; New York, NY, USA :
Cambridge University Press,
1996.
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| Series: | Cancer, clinical science in practice.
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| Subjects: |
Table of Contents:
- Aspects of hemopoiesis and the immune system important for cell therapy
- Overview of hemopoiesis and hempoietic reconstruction
- Effector cells of experimental and clinical cellular adoptive immunobiology
- Hemopoietic cell therapy
- Scientific principles
- Current and potential uses of defined cell populations
- Human progenitor cell assays
- Flow cytometric techniques
- Principles of gene therapy
- Technology of cell collection and preparation
- Sources of hemopoietic progenitor cells for transplantation.
- Chemotherapy-based approaches to mobilization of progenitor cells
- Cytokine-only approaches to mobilization of progenitor cells
- Characterization and isolation of mobilized peripheral blood stems cells using a high-speed cell sorter
- Hemopoietic stem cell selection using monoclonal antibodies
- Magnetic approaches to cell separation
- Growth factors and ex vivo expansion of hemopoietic progenitor cells
- Bioreactors for expansion
- Purging of malignant cells
- Current clinical approaches.
- Dose-intensive chemotherapy without hemopoietic cell support
- Clinical potential of hemopoietic growth-factor support for high-dose chemotherapy
- Treatment of solid tumors with high-dose chemotherapy requiring cellular support
- High-dose chemotherapy with cellular support for hematological malignancies
- Allogeneic marrow transplantation as treatment for myeloid malignancies: why it works and how it might be improved
- Future clinical applications
- Clinical gene therapy.
- Gene therapy of enzyme and immune deficiencies in the hemopoietic system
- Cellular therapy approaches to the treatment of AIDS
- Experimental and clinical cellular immunotherapy
- Adoptive immunotherapy with T cells
- Cellular adoptive immunotherapy with natural killer cells
- Autologous tumor cell vaccines
- Allogeneic cellular vaccines against tumors
- Neutrophil transfusions for treatment of infections
- Experimental and clinical cellular immunotherapy in bone-mararow transplantation.
- Donor lymphocyte therapy in bone-marrow transplantation.