Diagnostic and therapeutic antibodies /
| Other Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Totowa, N.J. :
Humana Press,
[2000]
|
| Series: | Methods in molecular medicine ;
40. |
| Subjects: |
Table of Contents:
- Pt. 1. Introduction
- The antibody molecule / Andrew J.T. George
- Polyclonal and monoclonal antibodies / Mary A. Ritter
- Engineering antibody molecules / Rakesh Verma, Ekaterini Boleti
- Phage display technology / Michael Johns
- Pt. 2. Antibodies in medicine
- Prospects for the application of antibodies in medicine / Herman Waldmann
- Antibodies for neoplastic disease: solid tumours / Ian T.W. Matthews
- The application of monoclonal antibodies in the treatment of lymphoma / Martin J. Glennie ... [et al.]
- Antibodies for inflammatory disease: effector cells / Richard Smith
- Antibodies for inflammatory disease: cytokines / Peter C. Taylor
- Antibodies for transplantation / Denise L. Faustman
- Antibody-based therapies in infectious diseases / H. Barbaros Oral, Cezmi A. Akdis̜
- Antibodies in nuclear medicine / A. Michael Peters
- Animal models for tumor localization / Gail Rowlinson-Busza
- Antibodies for immunoassays / David J. Newman
- Pt. 3. Ethics and industry
- Intellectual property / William M. Brown
- From laboratory to clinic: the story of CAMPATH-1 / Geoff Hale, Herman Waldmann
- Pt. 4. Production and purification
- Production of monoclonal antibodies / Jóna Freysdóttir
- Purification of monoclonal antibodies using protein A/G / Bridget Heelan
- Preparation of monoclonal antibodies using ion exchange chromatography / Maureen Power
- Quality control of raw materials / Patrick Harrison, Geoff Hale
- Cell banks and stability of antibody production / Pru Bird, Geoff Hale
- Measurement of endotoxin / Jenny Phillips, Patrick Harrison, Geoff Hale
- Aseptic vial filling / Kuldip Bhamra ... [et al.]
- Measurement of antibody concentrations by hemagglutination / Jenny Phillips, Geoff Hale
- Pt. 5. Clinical application of antibodies
- Enzymatic digestion of monoclonal antibodies / Sarah M. Andrew
- How to make bispecific antibodies / Ruth R. French
- Radiolabeling of monoclonal antibodies / Calvin S.R. Gooden
- Determination of the immunoreactivity of radiolabeled monoclonal antibodies / Gail Rowlinson-Busza
- Use of biosensors to measure the kinetics of antibody-antigen interactions / Andrew J.T. George
- Pt. 6. Application of antibodies in vitro
- How to set up an ELISA / Bill Jordan
- Measurement of HAMA and anti-idiotypic antibodies / Steve Nicholson
- SDS-PAGE and western blotting / Abdulhamid A. Al-Tubuly
- Flow cytometric analysis / Paul F. McKay
- Immunocytochemistry / Susan Van Noorden
- Immunolabeling for electron microscopy / Catherine E. Sarraf
- Pt. 7. Antibody engineering
- PCR of the V region / Rakesh Verma
- Phage display technology: protocols / Michael Johns, Donald B. Palmer.