Diagnostic and therapeutic antibodies /

Bibliographic Details
Other Authors: George, Andrew J. T., Urch, Catherine E.
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2000]
Series:Methods in molecular medicine ; 40.
Subjects:

MARC

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300 |a xiv, 477 pages :  |b illustrations ;  |c 24 cm. 
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490 1 |a Methods in molecular medicine ;  |v 40 
504 |a Includes bibliographical references and index. 
505 0 |a Pt. 1. Introduction -- The antibody molecule / Andrew J.T. George -- Polyclonal and monoclonal antibodies / Mary A. Ritter -- Engineering antibody molecules / Rakesh Verma, Ekaterini Boleti -- Phage display technology / Michael Johns -- Pt. 2. Antibodies in medicine -- Prospects for the application of antibodies in medicine / Herman Waldmann -- Antibodies for neoplastic disease: solid tumours / Ian T.W. Matthews -- The application of monoclonal antibodies in the treatment of lymphoma / Martin J. Glennie ... [et al.] -- Antibodies for inflammatory disease: effector cells / Richard Smith -- Antibodies for inflammatory disease: cytokines / Peter C. Taylor -- Antibodies for transplantation / Denise L. Faustman -- Antibody-based therapies in infectious diseases / H. Barbaros Oral, Cezmi A. Akdis̜ -- Antibodies in nuclear medicine / A. Michael Peters -- Animal models for tumor localization / Gail Rowlinson-Busza -- Antibodies for immunoassays / David J. Newman -- Pt. 3. Ethics and industry -- Intellectual property / William M. Brown -- From laboratory to clinic: the story of CAMPATH-1 / Geoff Hale, Herman Waldmann -- Pt. 4. Production and purification -- Production of monoclonal antibodies / Jóna Freysdóttir -- Purification of monoclonal antibodies using protein A/G / Bridget Heelan -- Preparation of monoclonal antibodies using ion exchange chromatography / Maureen Power -- Quality control of raw materials / Patrick Harrison, Geoff Hale -- Cell banks and stability of antibody production / Pru Bird, Geoff Hale -- Measurement of endotoxin / Jenny Phillips, Patrick Harrison, Geoff Hale -- Aseptic vial filling / Kuldip Bhamra ... [et al.] -- Measurement of antibody concentrations by hemagglutination / Jenny Phillips, Geoff Hale -- Pt. 5. Clinical application of antibodies -- Enzymatic digestion of monoclonal antibodies / Sarah M. Andrew -- How to make bispecific antibodies / Ruth R. French -- Radiolabeling of monoclonal antibodies / Calvin S.R. Gooden -- Determination of the immunoreactivity of radiolabeled monoclonal antibodies / Gail Rowlinson-Busza -- Use of biosensors to measure the kinetics of antibody-antigen interactions / Andrew J.T. George -- Pt. 6. Application of antibodies in vitro -- How to set up an ELISA / Bill Jordan -- Measurement of HAMA and anti-idiotypic antibodies / Steve Nicholson -- SDS-PAGE and western blotting / Abdulhamid A. Al-Tubuly -- Flow cytometric analysis / Paul F. McKay -- Immunocytochemistry / Susan Van Noorden -- Immunolabeling for electron microscopy / Catherine E. Sarraf -- Pt. 7. Antibody engineering -- PCR of the V region / Rakesh Verma -- Phage display technology: protocols / Michael Johns, Donald B. Palmer. 
650 2 |a Antibodies, Monoclonal  |x diagnostic use. 
650 2 |a Antibodies, Monoclonal  |x therapeutic use. 
650 2 |a Immunotherapy  |x methods. 
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700 1 |a Urch, Catherine E. 
830 0 |a Methods in molecular medicine ;  |v 40. 
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