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Molecular virology /

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Bibliographic Details
Main Author: Harper, David R. (David Richard)
Other Authors: Kinchington, Paul R.
Format: Book
Language:English
Published: Oxford : New York : Bios ; Published in the US and Canada by Springer, 1998.
Edition:Second edition.
Series:Medical perspectives series.
Subjects:
Viruses.
Antiviral Agents.
Immunity.
Table of Contents:
  • Virus structure and replication
  • What is a virus?
  • Virus classification
  • Virus structure
  • Virus replication
  • Effects of virus infection of the host cell
  • Types of virus infection
  • Viral transformation and oncogenesis
  • Sub-viral infections
  • Further reading
  • Electronic resources
  • Viral interactions with the immune system
  • The non-specific immune response
  • The cell-mediated immune response
  • The serological immune response
  • Apoptosis
  • The role of co-stimulation in the immune response
  • Evasion of immune surveillance
  • Epitope mapping
  • Production of specific antisera
  • Passive immunity
  • Further reading
  • Electronic resources
  • Vaccines and immunotherapy
  • Current vaccines
  • Adjuvants
  • Approaches to vaccine development
  • Possible pathogenic effects of biotechnology-derived vaccines
  • Tailoring of the immune response to vaccination
  • Alternative delivery systems
  • Therapeutic vaccination
  • Further reading
  • Electronic resources
  • Antiviral drugs
  • The history of antiviral drug development
  • Current antiviral drugs
  • Resistance to antiviral drugs
  • Combination therapy
  • Interferons
  • Development of antiviral drugs
  • Nucleic acid-based approaches to antiviral drug development
  • Further reading
  • Electronic resources
  • Cloning and gene therapy
  • Viruses and cloning
  • Construction of a plasmid vector
  • Cloning of viral genes
  • Expression in eukaryotic cells
  • Viral vector systems
  • Gene therapy
  • Further reading
  • Electronic resources
  • Molecular diagnostics
  • Immunological assays
  • Nucleic acid detection and amplification
  • Future developments in diagnostic virology
  • Further reading
  • Electronic resources
  • New and emerging viruses
  • Where do new or emerging viruses come from?
  • What factors contribute to disease emergence?
  • Monitoring emerging infectious diseases
  • Further reading
  • Electronic resources
  • Appendix A. Glossary.