Crystallographic methods and protocols /

Bibliographic Details
Other Authors:	Jones, Christopher, 1954-, Mulloy, Barbara, Sanderson, Mark R.
Format:	Book
Language:	English
Published:	Totowa, N.J. : Humana Press, [1996]
Series:	Methods in molecular biology (Clifton, N.J.) ; v. 56.
Subjects:	Proteins > chemistry. Nucleic Acids > chemistry. Crystallography, X-Ray > methods.

Table of Contents:

Introduction
Overexpression, isolation and crystallization of proteins
Preliminary characterization of crystals
Modern methods for rapid x-ray diffraction data collection from crystals of macromolecules
Use of multiple-wavelength anomalous diffraction measurements in Ab inition phase determination for macromolecular structures
Structure determination using isomorphous replacement
Molecular replacement using known structural data
Density modification in x-ray crystallography
Refinement of protein and nucleic acid structures
Recent developments for crystallographic refinement of macromolecules
The crystallization and structures analysis of oligonucleotide sequences
Crystallography in the study of protein-DNA interactions
Virus crystallography
Crystallization and structure analysis of membrane proteins