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Designing antibodies /

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Bibliographic Details
Main Author: Mayforth, Ruth D.
Format: Book
Language:English
Published: San Diego : Academic Press, Inc., [1993]
Subjects:
Antibodies > genetics.
Antibodies > therapeutic use.
Drug Design.
Genetic Engineering.
Table of Contents:
  • Antibody overview
  • Humoral immune system
  • Antibody structure
  • Functions of antibodies
  • Biosynthesis of immunoglobulins
  • Making monoclonal antibodies
  • Hybridoma technology
  • Making human monoclonal antibodies
  • Generating transfectomas
  • Immunoglobulin gene expression librarians
  • Generating epitope libraries
  • Designing antibodies for human therapy
  • Genetically engineered rodent-human antibodies
  • Genetically engineered antibodies lacking Fc reactivity
  • Novel recombinant antibody fusion proteins
  • Antibody targeting
  • Immunotoxins
  • Antibody-effector molecule conjugates
  • Antibodies with dual specificities
  • Antibody-targeted liposomes
  • Idiotypes and anti-idiotypic antibodies
  • Idiotypes and the idiotype network
  • Applications of anti-idiotypic antibodies
  • Catalytic antibodies
  • Enzyme kinetics and transition-state theory
  • Catalytic antibodies.