Novel therapeutic agents for the treatment of autoimmune diseases /
| Other Authors: | , , |
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| Format: | Book |
| Language: | English |
| Published: |
New York :
M. Dekker,
[1997]
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| Subjects: |
Table of Contents:
- 1. Introduction
- The evaluation of biological agents / Vibeke Strand and David L. Scott
- 2. Cellular targeted therapies
- Anti-CD5/ricin a chain immunoconjugate therapy in rheumatoid arthritis / John J. Cush
- Early clinical studies of IL-2 fusion toxin in patients with severe rheumatoid arthritis, recent-onset insulin-dependent diabetes mellitus, and psoriasis / Thasia G. Woodworth and Karen Parker
- Chimeric anti-CD4 antibody as a potential therapeutic agent for rheumatoid arthritis / Larry W. Moreland and William J. Koopman.
- CD4 monoclonal antibody therapy in rheumatoid arthritis / F.C. Breedveld
- The use of CE9.1, a primatized monoclonal anti-CD4, in the treatment of rheumatoid arthritis / David E. Yocum, Alan M. Solinger, and John A. Lipani
- CAMPATH-1H therapy in autoimmune diseases / Richard A. Watts and John D. Isaacs
- CAMPATH-1H in rheumatoid arthritis: United States experience / David E. Yocum and Jeffrey M. Johnston
- 3. Cytokine targeted therapies
- Interferon-gamma in the treatment of rheumatoid arthritis / Eric M. Veys, Herman Mielants, and Gust Verbruggen.
- Tumor necrosis factor blockade in rheumatoid arthritis / Michael J. Elliott, Marc Feldmann, and Ravinder N. Maini
- Engineered human anti-tumor necrosis factor-alpha (TNFα) antibody, CDP571, in rheumatoid arthritis / Ernest H.S. Choy and Gabriel S. Panayi
- Clinical experience with recombinant human interleukin-1 receptor type I (Rhu IL-1RI) in patients with rheumatoid arthritis / Richard M. Pope ... [et al.]
- Treatment of rheumatoid arthritis with soluble tumor necrosis factor receptor / Gary R. Margolies, William J. Koopman, and Larry W. Moreland.
- 4. Adhesion molecule targeted therapies
- Treatment of rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule-1 / Arthur F. Kavanaugh and Peter E. Lipsky
- 5. Potential antigen-specific therapies
- T-cell-receptor peptide therapy for multiple sclerosis / Arthur A. Vandenbark ... [et al.]
- T-cell-receptor peptide vaccination studies in rheumatoid arthritis / Louis W. Heck, Larry W. Moreland, and William J. Koopman
- Oral tolerance for the treatment of autoimmune disease / David A. Hafler and Howard L. Weiner
- Oral tolerance / David E. Trentham.
- Intravenous immunoglobulin (IVIg) in the treatment of autoimmune diseases / Vibeke Strand and Martin L. Lee
- 6. Purine and pyrimidine synthesis inhibitors
- Inhibitors of de novo nucleotide synthesis in the treatment of rheumatoid arthritis / Robert J. Fox and Randall E. Morris
- Leflunomide: a new immunosuppressive drug / David L. Scott and Vibeke Strand
- 7. Future directions
- An assessment of novel agents in the treatment of the rheumatic diseases / Vibeke Strand and Lee S. Simon.