Comparative pharmacokinetics : principles, techniques, and applications /
| Main Author: | |
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| Format: | Book |
| Language: | English |
| Published: |
Ames :
Iowa State University Press,
1999.
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| Edition: | First edition. |
| Subjects: |
Table of Contents:
- Principles of drug movement in the body
- Absorption
- Distribution
- Renal elimination
- Hepatic biotransformation and biliary excretion
- Compartmental models
- Noncompartmental models
- Nonlinear models
- Physiological models
- Dosage regimens
- Simultaneous pharmacokinetic-pharmacodynamic modeling
- Study design and data analysis
- Population pharmacokinetic models and Bayesian forecasting applied to clinical pharmacokinetics
- Dosage adjustments in renal disease
- Interspecies extrapolations
- Tissue residues and withdrawal times.