Capacitative calcium entry /

Bibliographic Details
Main Author: Putney, James W.
Format: Book
Language:English
Published: New York : Austin, [Tex.] : Chapman & Hall ; R.G. Landes, [1997]
Series:Molecular biology intelligence unit.
Subjects:

MARC

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245 1 0 |a Capacitative calcium entry /  |c James W. Putney, Jr. 
264 1 |a New York :  |b Chapman & Hall ;  |a Austin, [Tex.] :  |b R.G. Landes,  |c [1997] 
264 4 |c ©1997 
300 |a 210 pages, 1 page of plates :  |b illustrations (some color) ;  |c 27 cm. 
336 |a text  |2 rdacontent  |b txt 
337 |a unmediated  |2 rdamedia 
338 |a volume  |2 rdacarrier  |b nc 
490 1 |a Molecular biology intelligence unit 
504 |a Includes bibliographical references and index. 
505 0 |a Pt. 1. General aspects of calcium signaling -- The Concept of calcium as a cellular signal -- Measurement of cellular calcium levels and movements -- Calcium stores, calcium pools -- The Phosphoinositide story -- (145)IP3 receptors and intracellular Ca2 release -- Metabolism of inositol phosphates -- Calciosomes -- Intracellular calcium oscillations -- Excitable vs. nonexcitable cells -- Concluding remarks -- Pt. 2. Capacitative calcuim entry -- Biphasic calcium signaling -- The capacitative model is proposed.  
505 0 |a Proofs of the capacitative model: calcium overshoot, thapsigargin and Mn2 quench -- The Pathway for calcium entry -- Pt. 3. The Signal for capacitative calcium entry -- Conformational coupling -- Evidence against conformational coupling -- Evidence for a diffusible messenger for capacitative calcium entry -- Calcium as a signal for calcium entry -- Calcium influx factor (CIF) -- Metabolites of cytochrome P-450 -- Cyclic gmp -- (1,3,4,5,)IP4 -- Tyrosine kinase -- G-protein -- Conclusions.  
505 0 |a Pt. 4. Electrophysiology and regulation of capacitative calcium entry -- Properties of I -- Single channels -- Regulation of capacitative Ca2 entry channels by feedback inhibition -- Regulation of capacitative Ca2 entry channels by protein phosphorylation -- Conclusions -- Pt. 5. The Molecular nature of capacitative calcuim entry channels -- Drosophila trp and trpl -- Functional studies of expressed trp and trpl -- Mammalian homologs of trp -- Expression of mammalian trps -- A plasma membrane (1,4,5) IP3 receptor.  
505 0 |a Conclusions -- Pt. 5. Physiological, pharmacological and pathological aspects of capacitative calcium entry -- Physiological functions of capacitative calcium entry-short term responses -- Physiological functions of capacitative calcium entry-long term responses -- Pharmacology of capacitative calcium entry -- Clinical uses of inhibitors of capacitative calcium entry -- Pathology and toxicology of capacitative calcium entry -- conclusion.  
650 2 |a Calcium  |x metabolism. 
650 2 |a Calcium Channels  |x physiology. 
650 2 |a Electric Conductivity. 
650 2 |a Cell Membrane  |x physiology. 
650 2 |a Signal Transduction  |x physiology. 
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