Opioid peptides in substance abuse /
| Main Author: | |
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| Format: | Book |
| Language: | English |
| Published: |
Boca Raton :
CRC Press,
[1994]
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| Series: | CRC series in physiology of drug abuse.
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| Subjects: |
Table of Contents:
- Introduction: the pharmacological effects of [mu]- and [kappa]-agonists are divergent, in some aspects even opposite
- Aspecific character of the analgesia induced by [kappa]-agonists
- Antianalgesic effects of [kappa]-agonists
- [mu]-agonist induced euphoria as opposed to dysphoria elicited by [kappa]-agonists in humans and experimental animals
- Role of dopamine in the reinforcing effect of opiates
- Elements of a uniform brain reward circuitry
- Sensitization and the pathology of addiction
- Role of stress in addiction
- Altered genetic expression of endogenous opioids during addiction
- Mode of action of other abused substances
- Individual differences in propensity to drug addiction
- New strategies in the treatment of opiate and cocaine addiction.