Drugs, diet, and disease /
| Other Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
New York :
Ellis Horwood,
1995-
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| Series: | Ellis Horwood books in the biological sciences. Series in biochemistry and biotechnology.
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| Subjects: |
Table of Contents:
- v. 1. Mechanistic approaches to cancer.
- Mechanisms of chemical carcinogenesis and molecular parametric analysis in the safety evaluation of chemicals
- Metabolic generation of reactive intermediates
- The use of computers in evaluating the toxicity and carcinogenicity of chemicals
- Safety evaluation in the twenty-first century
- Reactive oxygen species in the aetiology of cancer
- ROS and chemical carcinogenesis
- Prospects for the future
- Carcinogens formed during cooking
- Isolation and chemical structure
- Formation
- Quantitation
- Genotoxicity
- Metabolism
- Binding to macromolecules
- Carcinogenicity
- Human significance
- Teratogenicity of pharmaceutical agents established as having carcinogenic effects: Review of effects and mechanisms
- Pharmaceutical agents recognized as carcinogenic.
- Sources of information on teratogenic effects
- Classification of evidence as to teratogenicity
- Review of possible teratogenic effects: Antineoplastic drugs
- Review of possible teratogenic effects: Hormonal preparations
- Review of possible teratogenic effects: Immunosuppressants
- Review of possible teratogenic effects: Analgesic mixtures containing phenacetin
- Mechanistic considerations
- Discussion and conclusion
- Mechanisms of anticarcinogenesis: The example of N-acetylcysteine
- Chemoprevention of cancer and other mutation-related diseases
- Mechanisms of inhibition of carcinogenesis, with special reference to N-acetylcysteine
- N-acetylcysteine: Biochemical and pharmacological issues
- Protective effects and mechanisms of N-acetylcysteine, as assessed in in vitro test systems
- Protective effects and mechanisms of N-acetylcysteine, as assessed in animal models
- Clinical trials in humans.
- Immunotherapy of cancer: Monoclonal antibodies
- Production of monoclonal antibodies
- Antibody structure and function
- General applications of monoclonal antibodies
- Monoclonal antibodies and cancer
- Monoclonal antibodies in diagnosis of cancer
- Monoclonal antibodies in therapy of cancer
- Antibody immunogenicity/ humanized antibodies
- Single chain antibodies
- Cancer genetics
- Phase I enzymes
- Phase II enzymes
- Combined polymorphisms
- Other genes involved in carcinogen metabolism
- Discussion
- Is folic acid pluripotent?
- Characteristics and sources of folic acid
- Consequences of frank deficiency
- Neural tube defects
- Other congenital anomalies
- Cancer
- Folate and other diseases
- Discussion and conclusions.