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Prion diseases of mammals and yeast : molecular mechanisms and genetic features /

Bibliographic Details
Main Author: Wickner, Reed B.
Format: Book
Language:English
Published: New York : Austin : Chapman & Hall ; R.G. Landes, [1997]
Series:Medical intelligence unit.
Subjects:
Prion Diseases.
Prions > genetics.
Yeasts > genetics.
Table of Contents:
  • History of transmissible spongiform encephalopathies
  • PrP - the prion protein
  • Transgenic and knockout mice
  • In vitro PrP-sen -> PrP-res conversion promoted by PrP-res
  • Structural studies of PrPsc and PrPc
  • Cell biology of PrP
  • Bovine spongiform encephalopathy ("mad cow disease")
  • Yeast prions
  • [URE3]
  • [PSI]
  • Comparison of the three prion systems
  • Conclusions: other possible prions and why prion diseases are so interesting