http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
World Congress on Alternatives and Animal Use in the Life Sciences : Education, Research, Testing
World Congress on Alternatives and Animal Use in the Life Sciences : Education, Research, Testing 1993 : Baltimore, Md.)
xxxv, 738 pages : illustrations ; 26 cm.
Replacement alternatives and the concept of alternatives -- The history of animal use in the life sciences -- The role of animals and alternatives in education -- Science, ethics, and animals -- The need to refine animal care and use -- Reduction of animal use and experimental design -- Alternatives in safety testing : progress or uselessness? -- Animals and society -- The development of legislation on the use of animals and alternatives -- W.M.S. Russell speech at the awards luncheon -- Picard's Dilemma (text of the play presented at the World Congress banquet) -- Heavy metals -- Neurobiology -- Reproductive toxicology -- Hepatic function and metabolism -- Biologicals -- Toxicity testing -- Dermal toxicology -- Ocular -- Renal toxicology -- Alternatives and risk assessment : a risk worth taking -- The chicken enucleated eye test (CEET) : a screen for the assessment of eye irritation/corrosion potential of compounds -- Alternatives in safety testing : approaches in the Slovak Republic -- Combining in vitro alternatives and physiologically-based computer modeling will improve quantitative health risk assessments
Structure-activity relationships as alternatives in the study of carcinogenesis -- Attempts to validate a possible predictive animal model for human erythrocyte G-6-PD deficiency -- Rat as a model to study postprandial effects in man -- Validation programs in Europe -- Observations on US validation studies -- Validation of new toxicology test systems-the paradigm of genetic toxicity tests -- Current status of validation studies in Japan -- The landscape of alternatives-AWIC -- The UC Center for animal alternatives -- The status of in vitro toxicity testing databases in Europe -- Public sources of in vitro toxicity testing data in North America -- The Galileo Data Bank of alternative methodologies to the use of animals in toxicity testing -- Reduction of the use of animals for quality control testing in the European Pharmacopoeia -- USP alternatives to animal testing : the in vitro option - a progress report
Education - the three R's concept -- Computers in education -- On the ethical and scientific need for assessing the potential benefit of research likely to cause suffering to protected animals -- Mechanisms of pain -- Euthanasia -- Environmental manipulations to promote psychological well-being in primates -- Animal boredom : consequences for housing and feeding conditions -- Refinement of perioperative care -- Refining anaesthetic techniques in a laboratory animal facility : practical problems -- Pain and distress in laboratory animals : what we know and what we assume -- Preclinical models for analgesic drug study -- Ethical scoring systems -- The Australian and New Zealand Council fo the care of animals in research and teaching -- The role of animal care committees in fostering use of alternatives : a case study -- The use of rabbits, dogs, cats, and primates in USDA-registered and federal biomedical laboratories in the United States 1975-1992
The psychology of animal rights activism -- The caring sleuth : a qualitative analysis of animal rights activists -- Public attitudes toward animal research : a comparative study of 15 nations -- On recognizing and overcoming barriers to the acceptance of alternative methods -- Progress in the acceptance of in vitro tests by regulatory authorities -- The erosion of acceptability of animal toxicity tests in the courtroom -- Directory of funding sources for scientific pursuit of alternatives -- Endpoints and cell systems for in vitro toxicity assessment : a discussion of specific target cell toxicity versus basal cytotoxicity -- In vitro and in vivo : alternative or complementary techniques?
editors, Alan M. Goldberg, L.F.M. van Zutphen ; editorial assistant, Marilyn L. Principe.
Proceedings of the first World Congress on Alternatives and Animal Use in the Life Sciences held in Baltimore, Nov. 14-19, 1993.
Alternative methods in toxicology and the life sciences ; v. 11