Human vaccines and vaccination /

Bibliographic Details
Main Author: Mackett, M.
Other Authors: Williamson, J. D.
Format: Book
Language:English
Published: Oxford : BIOS Scientific Publishers, 1995.
Series:Medical perspectives series.
Subjects:

MARC

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245 1 0 |a Human vaccines and vaccination /  |c M. Mackett, J.D. Williamson. 
264 1 |a Oxford :  |b BIOS Scientific Publishers,  |c 1995. 
264 2 |a Herndon, Va. :  |b Books International [distributor]. 
300 |a xv, 215 pages :  |b illustrations (some color) ;  |c 24 cm. 
336 |a text  |2 rdacontent  |b txt 
337 |a unmediated  |2 rdamedia 
338 |a volume  |2 rdacarrier  |b nc 
490 1 |a Medical perspectives series 
504 |a Includes bibliographical references and index. 
505 0 |a Communicable diseases: The problem and some solutions -- An overview of communicable diseases -- A short history of vaccine development: Jenner's legacy -- Vaccination practice in developed countries -- Vaccination practice in developing countries -- The need for new and improved vaccines -- References -- Etiological agents of communicable diseases requiring new or improved human vaccines -- Viruses -- Bacteria -- Chlamydia -- Parasitic protozoa -- Parasitic helminths -- Mechanisms of pathogenesis -- Anatomical sites used by pathogens to gain entry into the human body -- Localized infections -- Systemic infections -- Organs or tissues targeted by pathogens following their systemic spread -- Oncogenic virus infections -- Opportunistic virus infections -- Transmission of infectious diseases -- Innate and required immune responses.  
505 0 |a Innate responses to infection -- Acquired immune responses to infection -- Humoral immunity -- Cell-mediated immunity -- T lymphocytes -- Antigens -- Cytokines -- References -- Immune responses to infectious and parasitic diseases -- Innate immunity -- Acquired immunity -- Antigenic diversity. 
505 0 |a Antigenic complexity -- Latent infections -- Modulation of immune responses -- Immune evasion -- Anamnestic immune responses -- Protective immune responses -- References -- Identification and analysis of vaccine antigens -- The role of molecular biology in vaccine development -- Identification and cloning of antigens -- Characterization of vaccine antigens: B-cell epitopes -- Characterization of vaccine antigens: T-cell epitopes -- References -- Developing new vaccines: Inactivated and subunit approaches -- Inactivated vaccines -- Expression systems and subunit vaccines -- Peptide vaccines -- Anti-idiotypes -- Genetic immunization -- Issues of presentation -- References -- New and improved live attenuated vaccines -- Improving attenuation: Pseudorabies- a veterinary vaccine pardigm -- Improving attenuation: V. cholerae -- Improving stability: Poliovirus -- Recombinant live vectors -- Vaccinia virus recombinants.  
505 0 |a Cross-species vaccination: 'Live-dead' vaccines -- BCG -- Attenuated salmonella strains as live recombinant bacterial vaccines -- Poliovirus chimeras -- Other virus vectors -- Recombinant e. coli strains.  
505 0 |a Improving immunogenicity: Examples from vaccinia virus -- References -- EBV vaccine development: A laboratory-based case study -- Natural history and clinical significance of EBV -- Rationale for EBV program -- Vaccine design for EBV -- Identification and characterization of EBV antigens -- Vaccines based on gp340 -- References -- HBV vaccines- from the laboratory to license: A case study -- Epidemiology and disease in HBV infection -- HBV structure -- HBV vaccines -- Problems -- Further development -- Practical considerations: From laboratory to arm -- References -- Discussion -- Why vaccinate?- prevention is better than cure -- Herd immunity and its control of infectious and parasitic diseases -- Elimination of an infectious disease: Smallpox eradication -- The argument for expanded programs of immunization -- The need for new or improved vaccines -- Sterile immunity: Is it possible? -- New and re-emerging infectious diseases -- References.  
650 2 |a Vaccines. 
650 2 |a Vaccination. 
650 2 |a Immunotherapy, Active. 
650 2 |a Communicable Diseases  |x immunology. 
700 1 |a Williamson, J. D. 
830 0 |a Medical perspectives series. 
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