Quality assurance handbook for veterinary laboratories /
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| Other Authors: | |
| Format: | Book |
| Language: | English |
| Published: |
Ames :
Iowa State University Press,
2000.
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| Edition: | First edition. |
| Subjects: |
Table of Contents:
- Ch. 1. Introduction
- Overview of a laboratory quality assurance program
- The laboratory quality manual: a framework for quality assurance
- Value of a laboratory quality assurance program
- Ch. 2. Quality goals
- Analytic error and allowable error
- Selecting quality goals
- Ch. 3. Mathematical concepts for quality assurance
- Measures of central tendency
- Measures of variation
- Data distribution
- Confidence intervals
- Accuracy, precision, and allowable error
- Ch. 4. Monitoring for quality
- Internal monitoring - quality control
- Continuous (interval or ratio scale) measurements
- Selecting and preparing quality control materials
- Calculating control limits and target means
- Levey-Jennings control charts
- Which control rules and how many controls?
- Errors and corrective actions for rejection rules
- Calibrators, controls, reagents, and instruments
- Definitive and reference methods and reference materials
- Categorical (nominal scale) measurements
- Controls and inspections
- Internal audits for quality assessment
- External monitoring - proficiency testing
- Ch. 5. Quality of operations, policies, and resources
- Mandate, services, clients, organizational structure, and budget
- Policies, procedures, and laboratory management
- Laboratory and equipment
- Financial management
- Causes and control of preanalytic variation
- Handling of reagents and supplies
- Handling of specimens
- Random and cyclic biological variations
- Diet-, stress-, and exercise-induced variation
- Variations from technique of specimen collection
- Variations from hemolysis and intravenous fluids
- Labeling specimens
- Transportation, centrifugation, and storage
- Rejection of specimens
- Records of reagent and specimen handling
- Chain-of-custody considerations
- Laboratory information systems
- Main features of the system
- Patient identification
- Test order entry
- Specimen identification and tracking
- Interfaces with analytic instruments
- Entering results into the system
- Reporting results from the system
- Archives and data retention
- Quality assurance and management aspects of the system
- Security of laboratory information
- Standard analytic procedures
- Standard screening of reports
- Interpretation of laboratory tests
- Ch. 6. Evaluating laboratory procedures
- Evaluating the practicality and potential value
- Evaluating the analytic characteristics
- Within-run precision
- Reportable range, linearity, and sensitivity
- Accuracy and recovery
- Specificity and interference
- Run-to-run precision
- Comparison-of-methods study
- Correlation and regression statistics for method comparisons
- Evaluating the medical characteristics
- Medical justification for a test
- Medical characteristics of a test
- Reference values
- Documenting the procedure and informing clients
- Ch. 7. Laboratory choices and point-of-care testing
- Chemistry
- Hematology
- Coagulation
- Cytopathology and parasitology
- Bacteriology, histopathology, and therapeutic drug analysis
- Point-of-care testing.