The use of short- and medium-term tests for carcinogens and data on genetic effects in carcinogenic hazard evaluation /

Bibliographic Details
Corporate Authors:	International Agency for Research on Cancer, World Health Organization, Symposium on the Use of Short- and Medium-term Tests for Carcinogens and Data on Genetic Effects in Carcinogenic Hazard Evaluation
Other Authors:	McGregor, D., Rice, Jerry M., Venitt, S.
Format:	Conference Proceeding Book
Language:	English
Published:	Lyon, France : Oxford, International Agency for Research on Cancer ; 1999.
Series:	IARC scientific publications ; no. 146.
Subjects:	Carcinogenicity Tests > Congresses. Data Collection > Congresses. Mutagenicity Tests > Congresses. Risk Assessment > Congresses. Animals, Laboratory > Congresses.

Table of Contents:

Consensus report
Mutations and altered expression of human cancer genes: what they tell us about causes / T.R. Devereux, J.I. Risinger, J.C. Barrett
Analysis of somatic mutations of the p53 gene in human cancers: a tool to generate hypotheses about the natural history of cancer / T. Hernandez-Boussard, R. Montesano, P. Hainaut
Mutations in ras genes in experimental tumours of rodents / R.C. Sills ... [et al.]
Mutation patterns in non-ras oncogenes and tumour suppressor genes in experimentally induced tumours / A.O. Perantoni, J.M. Rice
Genetically altered mouse models for identifying carcinogens / R.W. Tennant ... [et al.]
Use of non-mammalian species in bioassays for carcinogenicity / T.E. Bunton
Chemically induced preneoplastic lesions in rodents as indicators of carcinogenic activity / G.M. Williams
Short- and medium-term carcinogenicity tests: simple initiation-promotion assay systems / H. Tsuda, C.B. Park, M.A. Moore
Medium-term bioassays in rats for rapid detection of the carcinogenic potential of chemicals / T. Shirai, M. Hirose, N. Ito
Active cell death (apoptosis) and cellular proliferation as indicators of exposure to carcinogens / R. Schulte-Hermann ... [et al.]
DNA adducts in mammalian cells as indicators of exposure to carcinogens / D.E.G. Shuker
DNA damage and repair in mammalian cells in vitro and in vivo as indicators of exposure to carcinogens / D. McGregor, D. Anderson
Mutation in mammalian cells in vitro and in vivo as indicators of exposure to carcinogens / A.A. van Zeeland, H. Vrieling
Induction of mutations in transgenic animal models: BigBlue and MutaMouse / P. Schmezer, C. Eckert
Chromosomal changes / R.J. Preston
Use of Syrian hamster embryo and BALB/c 3T3 cell transformation for assessing the carcinogenic potential of chemicals / R.A. LeBoeuf ... [et al.]
The results of assays in Drosophila as indicators of exposure to carcinogens / E.W. Vogel ... [et al.]
Use of tests in yeasts and fungi in the detection and evaluation of carcinogens / J.M. Parry
Identification of carcinogenic substances by means of short-term tests in bacteria / P. Quillardet, D. McGregor
Short-term tests for defining mutagenic carcinogens / M.D. Waters, H.F. Stack, M.A. Jackson.