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| LEADER |
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| 001 |
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| 005 |
20191203081738.0 |
| 008 |
000411s1999 fr a b 001 0 eng d |
| 020 |
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|a 9283221508
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| 035 |
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|a (OCoLC)43798694
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| 035 |
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|z (UtOrBLW)27739
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|a 41923
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|a OS2
|c OS2
|d UtOrBLW
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| 049 |
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|a TMVM
|c 1
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| 096 |
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|a QZ 202
|b E96 1999
|
| 245 |
0 |
0 |
|a Exocyclic DNA adducts in mutagenesis and carcinogenesis /
|c edited by B. Singer and H. Bartsch.
|
| 264 |
|
1 |
|a Lyon :
|b International Agency for Research on Cancer,
|c 1999.
|
| 300 |
|
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|a xvi, 361 pages :
|b illustrations (some color) ;
|c 25 cm.
|
| 336 |
|
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|a text
|2 rdacontent
|b txt
|
| 337 |
|
|
|a unmediated
|2 rdamedia
|
| 338 |
|
|
|a volume
|2 rdacarrier
|b nc
|
| 490 |
1 |
|
|a IARC scientific publications ;
|v no. 150
|
| 500 |
|
|
|a "World Health Organization"--Cover and title page.
|
| 500 |
|
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|a Foreword: "...a second international conference was held at the Deutsches Krebsforschungzentrum (DKFZ) in Heidelberg in September 1998...The presentations which resulted in this volume...".
|
| 504 |
|
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|a Includes bibliographical references and index.
|
| 505 |
0 |
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|a Keynote address: Exocyclic adducts as new risk markers for DNA damage in man / H. Bartsch -- Ch. 1. Occurrence and methods of detection -- Chemistry and biology of DNA damage by malondialdehyde / L.J. Marnett -- Formation and repair of DNA adducts in vinyl chloride- and vinyl fluoride-induced carcinogenesis / J.A. Swenberg ... [et al.] -- Role of 1,N²-propanodeoxyguanosine adducts as endogenous DNA lesions in rodents and humans / F.-L. Chung ... [et al.] -- Lipid peroxidation-induced etheno-DNA adducts in humans / J. Nair -- Detection of 1, N⁶-etheno-2́-deoxyadenosine and 3,N⁴-etheno-2́-deoxycytidine occurring endogenously in DNA / W.P. Watson ... [et al.] -- Ch. 2. Chemistry -- Possible mechanisms of carcinogenesis after exposure to benzene / B.T. Golding, W.P. Watson -- Synthesis of para-benzoquinone and 1,3-bis(2-chloroethyl)nitrosourea adducts and their incorporation into oligonucleotides / A. Chenna, H. Maruenda, B. Singer -- Purine DNA adducts of 4,5-dioxovaleric acid and 2,4-decadienal / J. Cadet ... [et al.] -- Adducts of chlorohydroxyfuranones and of aldehyde conjugates / L. Kronberg ... [et al.] -- Cyclic adducts and intermediates induced by simple epoxides / J.J. Solomon -- Ch. 3. Formation from exogenous and endogenous sources -- Formation of etheno adducts and their effects on DNA polymerases / F.P. Guengerich ... [et al.] -- Reactions of α-acetoxy-N-nitrosopyrrolidine and crotonaldehyde with DNA / S.S. Hecht, P. Upadhyaya, M. Wang -- Glyoxal-guanine DNA adducts: detection, stability and formation in vivo from nitrosamines / R.N. Loeppky ... [et al.] -- Ch. 4. Physiochemical approaches to structural elucidation -- Effects of 3,N⁴-etheno-deoxycytidine on duplex stability and energetics / G.E. Plum, C.A. Gelfand, K.J. Breslauer -- Solution structures of DNA duplexes containing the exocyclic lesion 3,N⁴-etheno-2́-deoxycytidine / D. Cullinan, M. Eisenberg, C. de los Santos -- Thermal destabilization of DNA oligonucleotide duplexes by exocyclic adducts on adenine or cytosine depends on both the base and the size of the adduct / J. Sági, B. Singer -- Ch. 5. Cyclic adducts as biomarkers -- A sensitive immunoslot-blot assay for detection of malondialdehyde-deoxyguanosine in human DNA / C. Leuratti ... [et al.] -- ³²P-postlabelling with high-performance liquid chromatography for analysis of abundant DNA adducts in human tissues / K. Yang ... [et al.] -- Cancer risk assessment for crotonaldehyde and 2-hexenal: an approach / E. Eder, D. Schuler, Budiawan -- Ch. 6. DNA repair and effects on replication -- Mammalian enzymatic repair of etheno and para-benzoquinone exocyclic adducts derived from the carcinogens vinyl chloride and benzene / B. Singer, B. Hang -- Enzymology of the repair of etheno adducts in mammalian cells and in Eschericia coli / M. Saparbaev, J. Laval -- Cellular response to exocyclic DNA adducts / M. Moriya ... [et al.] -- Role of base excision repair in protecting cells from the toxicity of chloroethylnitrosoureas / D.B. Ludlum, Q. Li, Z. Matijasevic -- Localization of chloroacetaldehyde-induced DNA damage in human p53 gene by DNA polymerase fingerprint analysis / B. Tudek, P. Kowalczyk, J.M. Cieúla -- Ch. 7. Mutagenesis and carcinogenesis -- Cancer-prone oxyradical overload disease / S. Ambs ... [et al.] -- Role of etheno DNA adducts in carcinogenesis induced by vinyl chloride in rats / A. Barbin -- Vinyl chloride-specific mutations in humans and animals / M.J. Marion, S. Boivin-Angele -- Solution conformation and mutagenic specificity of 1,N⁶-ethenoadenine / A.K. Basu, J.M. McNulty, W.G. McGregor -- Genetic effects of exocyclic DNA adducts in vivo: heritable genetic damage in comparison with loss of heterozygosity in somatic cells / M.J.M. Nivard, E.W. Vogel -- Appendix: Distortion of the double helix by para-benzoquinone adducts / J. Sági, B. Singer.
|
| 650 |
|
2 |
|a DNA Adducts.
|
| 650 |
|
2 |
|a Carcinogens.
|
| 650 |
|
2 |
|a Mutagens.
|
| 650 |
|
2 |
|a DNA Repair.
|
| 700 |
1 |
|
|a Bartsch, H.
|
| 700 |
1 |
|
|a Singer, B.
|q (Beatrice),
|d 1922-
|
| 710 |
2 |
|
|a International Agency for Research on Cancer.
|
| 710 |
2 |
|
|a World Health Organization.
|
| 830 |
|
0 |
|a IARC scientific publications ;
|v no. 150.
|
| 999 |
|
|
|a MARS
|
| 999 |
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| 952 |
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|p ric
|a Texas A&M University
|b Rellis Campus
|c Joint Library Facility
|d Remote Storage
|t 0
|e QZ 202 E96 1999
|h National Library of Medicine classification
|i unmediated -- volume
|m 3238901656606
|
| 998 |
f |
f |
|a QZ 202 E96 1999
|t 0
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|