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Human molecular genetics 2 /

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Bibliographic Details
Main Author: Strachan, T.
Other Authors: Read, Andrew P., 1939-
Format: Book
Language:English
Published: New York : Wiley-Liss, 1999.
Edition:Second edition.
Subjects:
Molecular Biology.
Genetic Predisposition to Disease.
Genetics, Medical.
Chromosome Mapping.
Table of Contents:
  • DNA structure and gene expression
  • Chromosomes in cells
  • Genes in pedigrees
  • Cell-based DNA cloning
  • Nucleic acid hybridization assays
  • PCR, DNA sequencing and in vitro mutagenesis
  • Organization of the human genome
  • Human gene expression
  • Instability of the human genome : mutation and DNA repair
  • Physical and transcript mapping
  • Genetic mapping of mendelian characters
  • Genetic mapping of complex characters
  • Genome projects
  • Our place in the tree of life
  • Identifying human disease genes
  • Molecular pathology
  • Genetic testing in individuals and populations
  • Cancer genetics
  • Complex diseases : theory and results
  • Studying human gene structure, expression and function using cultured cells and cell extracts
  • Genetic manipulation of animals
  • Gene therapy and other molecular genetic-based therapeutic approaches