The squid giant synapse : a model for chemical transmission /

Bibliographic Details
Main Author: LlinĂ¡s, Rodolfo R. (Rodolfo Riascos), 1934-
Format: Book
Language:English
Published: New York : Oxford University Press, 1999.
Subjects:
Table of Contents:
  • Ch. 1. Introduction
  • Historical background
  • Overview of synaptic transmission
  • The squid giant synapse
  • Ch. 2. Electrophysiological studies
  • Early electrophysiological studies
  • Synaptic transmission without action potentials
  • Presynaptic calcium influx and transmitter release
  • Electrophysiological properties of the postsynaptic potential
  • Appendix: noise analysis
  • Ch. 3. Presynaptic calcium current and transmitter release
  • Presynaptic voltage-clamp studies
  • Voltage clamp with a simulated action potential waveform
  • Presynaptic calcium injections and transmitter release
  • Temperature effects
  • Voltage dependence of transmitter release
  • A mathematical model for synaptic transmission
  • Synaptic plasticity
  • Calcium concentration microdomains
  • Summary
  • Ch. 4. Molecular mechanisms
  • Predocking events
  • Vesicular docking and availablility
  • Vesicular fusion and exocytosis
  • Summary
  • Ch. 5. Toxins and transmitter release
  • The clostridial toxins
  • Tetanus toxin and synaptobrevin
  • Botulinum C toxin and syntaxin
  • Calcium blockers and synaptic transmission
  • Summary
  • Ch. 6. Peptides and kinases
  • FMRFamide-related peptides
  • Tyrosine kinase
  • Ch. 7. Concluding remarks
  • Appendix A: The mathematical model for synaptic transmission
  • Appendix B: A computer model for synaptic transmission.