The squid giant synapse : a model for chemical transmission /
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| Format: | Book |
| Language: | English |
| Published: |
New York :
Oxford University Press,
1999.
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| Subjects: |
Table of Contents:
- Ch. 1. Introduction
- Historical background
- Overview of synaptic transmission
- The squid giant synapse
- Ch. 2. Electrophysiological studies
- Early electrophysiological studies
- Synaptic transmission without action potentials
- Presynaptic calcium influx and transmitter release
- Electrophysiological properties of the postsynaptic potential
- Appendix: noise analysis
- Ch. 3. Presynaptic calcium current and transmitter release
- Presynaptic voltage-clamp studies
- Voltage clamp with a simulated action potential waveform
- Presynaptic calcium injections and transmitter release
- Temperature effects
- Voltage dependence of transmitter release
- A mathematical model for synaptic transmission
- Synaptic plasticity
- Calcium concentration microdomains
- Summary
- Ch. 4. Molecular mechanisms
- Predocking events
- Vesicular docking and availablility
- Vesicular fusion and exocytosis
- Summary
- Ch. 5. Toxins and transmitter release
- The clostridial toxins
- Tetanus toxin and synaptobrevin
- Botulinum C toxin and syntaxin
- Calcium blockers and synaptic transmission
- Summary
- Ch. 6. Peptides and kinases
- FMRFamide-related peptides
- Tyrosine kinase
- Ch. 7. Concluding remarks
- Appendix A: The mathematical model for synaptic transmission
- Appendix B: A computer model for synaptic transmission.