Central nervous system diseases : innovative animal models from lab to clinic /
| Other Authors: | , , |
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| Format: | Book |
| Language: | English |
| Published: |
Totowa, N.J. :
Humana Press,
[2000]
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| Series: | Contemporary neuroscience.
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| Subjects: |
Table of Contents:
- Pt. 1. Aging and Alzheimer's disease
- The cholinergic hypothesis a generation later: perspectives gained on the use and integration of animal models / Raymond T. Bartus
- Patterns of cognitive decline in the aged rhesus monkey / Mark B. Moss, Ronald J. Killiany, James G. Herndon
- Cholinergic lesions as a model of Alzheimer's disease: effects of nerve growth factor / James M. Conner, Mark H. Tuszynski
- The immunolesioned animal as a model of transmitter dysfunction / Gary L. Wenk
- An intracerebral tumor necrosis factor-α infusion model for inflammation in Alzheimer's disease / Kimberly B. Bjugstad, Gary W. Arendash
- The senescence-accelerated mouse as a possible animal model of senile dementia / Yasuyuki Nomura, Yasunobu Okuma, Yoshihisa Kitamura
- Transgenic mice overexpressing presenilin cDNAs: phenotype and utility in the modeling of Alzheimer's disease / Karen Duff
- Pt. 2. Parkinson's disease
- Intervention strategies for degeneration of dopamine neurons in Parkinsonism: optimizing behavioral assessment of outcome / Timothy Schallert, Jennifer L. Tillerson
- Development of behavioral outcome measures for preclinical Parkinson's research / Mark D. Lindner
- Behavioral assessment in the unilateral dopamine-depleted marmoset / L.E. Annett ... [et al.]
- Molecules for neuroprotection and regeneration in animal models of Parkinson's disease / O. Isacson, L.C. Costantini, W.R. Galpern
- Antisense knockdown of dopamine receptors / Simranjit Kaur, Ian Creese
- Is trophic factor gene disruption a "knockout" model for Parkinson's disease? / Ann-Charlotte Granholm, Barry Hoffer
- Pt. 3. Huntington's disease
- Operant analysis of striatal dysfunction / Peter J. Brasted ... [et al.]
- Intrastriatal injections of quinolinic acid as a model for developing neuroptrotective strategies in Huntington's disease / Dwaine F. Emerich
- Systemic administration of 3-nitropropionic acid: a new model of Huntington's disease in rat
- Emmanuel Brouillet, Philippe Hantraye, M. Flint Beal
- Replicating Huntington disease's phenotype in nonhuman primates / Philippe Hantraye ... [et al.]
- Transgenic mouse models of Huntington's disease / Gillian P. Bates, Laura Mangiarini, Stephen W. Davies
- Pt. 4. Traumatic brain injury and stroke
- Rigid indentation models of traumatic brain injury in the rat / Richard L. Sutton
- Rodent ischemia models of embolism and ligation of the middle cerebral artery: clinical relevance to treatment strategies of stroke / Cesario V. Borlongan ... [et al.]
- A primate model of hypertensive cerebrovascular disease / Mark B. Moss
- Pt. 5. Innovations leading to clinical therapy
- Nictotinic therapeutics for Tourette syndrome and other neuropsychiatric disorders: from laboratory to clinic / R. Dough Shytle ... [et al.]
- Neural grafting for Parkinson's and Huntington's disease / Ben Roitberg ... [et al.]
- Future prospects of gene therapy for treating CNS diseases / Daniel A. Peterson, Jasodhara Ray, Fred H. Gage.