http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
innovative animal models from lab to clinic
Pt. 1. Aging and Alzheimer's disease -- The cholinergic hypothesis a generation later: perspectives gained on the use and integration of animal models / Raymond T. Bartus -- Patterns of cognitive decline in the aged rhesus monkey / Mark B. Moss, Ronald J. Killiany, James G. Herndon -- Cholinergic lesions as a model of Alzheimer's disease: effects of nerve growth factor / James M. Conner, Mark H. Tuszynski -- The immunolesioned animal as a model of transmitter dysfunction / Gary L. Wenk -- An intracerebral tumor necrosis factor-α infusion model for inflammation in Alzheimer's disease / Kimberly B. Bjugstad, Gary W. Arendash -- The senescence-accelerated mouse as a possible animal model of senile dementia / Yasuyuki Nomura, Yasunobu Okuma, Yoshihisa Kitamura -- Transgenic mice overexpressing presenilin cDNAs: phenotype and utility in the modeling of Alzheimer's disease / Karen Duff -- Pt. 2. Parkinson's disease -- Intervention strategies for degeneration of dopamine neurons in Parkinsonism: optimizing behavioral assessment of outcome / Timothy Schallert, Jennifer L. Tillerson -- Development of behavioral outcome measures for preclinical Parkinson's research / Mark D. Lindner -- Behavioral assessment in the unilateral dopamine-depleted marmoset / L.E. Annett ... [et al.] -- Molecules for neuroprotection and regeneration in animal models of Parkinson's disease / O. Isacson, L.C. Costantini, W.R. Galpern -- Antisense knockdown of dopamine receptors / Simranjit Kaur, Ian Creese -- Is trophic factor gene disruption a "knockout" model for Parkinson's disease? / Ann-Charlotte Granholm, Barry Hoffer -- Pt. 3. Huntington's disease -- Operant analysis of striatal dysfunction / Peter J. Brasted ... [et al.] -- Intrastriatal injections of quinolinic acid as a model for developing neuroptrotective strategies in Huntington's disease / Dwaine F. Emerich -- Systemic administration of 3-nitropropionic acid: a new model of Huntington's disease in rat -- Emmanuel Brouillet, Philippe Hantraye, M. Flint Beal -- Replicating Huntington disease's phenotype in nonhuman primates / Philippe Hantraye ... [et al.] -- Transgenic mouse models of Huntington's disease / Gillian P. Bates, Laura Mangiarini, Stephen W. Davies -- Pt. 4. Traumatic brain injury and stroke -- Rigid indentation models of traumatic brain injury in the rat / Richard L. Sutton -- Rodent ischemia models of embolism and ligation of the middle cerebral artery: clinical relevance to treatment strategies of stroke / Cesario V. Borlongan ... [et al.] -- A primate model of hypertensive cerebrovascular disease / Mark B. Moss -- Pt. 5. Innovations leading to clinical therapy -- Nictotinic therapeutics for Tourette syndrome and other neuropsychiatric disorders: from laboratory to clinic / R. Dough Shytle ... [et al.] -- Neural grafting for Parkinson's and Huntington's disease / Ben Roitberg ... [et al.] -- Future prospects of gene therapy for treating CNS diseases / Daniel A. Peterson, Jasodhara Ray, Fred H. Gage.
edited by Dwaine F. Emerich, Reginald L. Dean III, Paul R. Sanberg.
Includes bibliographical references and index.