Microbial pathogenesis : a principles-oriented approach /

Bibliographic Details
Other Authors: McClane, Bruce A., Mietzner, Timothy A.
Format: Book
Language:English
Published: Madison, Conn. : Fence Creek Publishing, [1999]
Series:Integrated medical sciences.
Subjects:
Table of Contents:
  • Pt. 1. Introduction to the infectious diseases
  • Biology of microbial pathogens
  • Bacterial growth and physiology
  • Growth of viruses
  • Antimicrobial therapy
  • Resistance to antimicrobial agents / Saleem A. Khan
  • Pt. 2. Establishment of infectious diseases: transmission and colonization
  • Infectious diseases acquired by ingestion
  • Pathogens acquired by inhalation
  • Zoonotic infections
  • Sexually transmitted diseases / William F. Goins
  • Bloodborne and transplant-associated infections
  • Normal microbial flora inhibition of colonization
  • Colonization I: adherence
  • Colonization II: invasion
  • Pt. 3. Microbial subversion of host defenses
  • Overcoming the physical and chemical defenses of the human body
  • Immune survival strategies of intracellular prokaryotic and eukaryotic pathogens
  • Immune evasion strategies: molecular mimicry
  • Immune evasion strategies: antigenic variation
  • Immune evasion strategies: capsules
  • Immune evasion strategies of bacteria: noncapsular surface factors and secreted factors
  • Pt. 4. Mechanisms by which pathogens damage the host
  • Bacterial exotoxins
  • Sepsis / Karen A. Norris
  • Immunopathologic consequences of inflammation / Joanne L. Flynn
  • Pt. 5. Genetics of microbial virulence
  • Role of mobile genetic elements in bacterial virulence
  • Regulation of bacterial virulence factor expression
  • Pt. 6. Host factors and the outcome of infection
  • Consequences of failure to clear pathogens: persistence, latency, and the carrier state / William F. Goins
  • Role of bacteria and viruses in tumorigenesis
  • Acquired immunodeficiency syndrome
  • Opportunistic infections
  • Pt. 7. Vaccine principles
  • Bacterial and viral vaccines
  • Appendixes
  • Diagnostic medical microbiology
  • Control of pathogens by sterilization, pasteurization, and disinfection
  • Table: Review of medically important pathogens.